Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10697335 | 0.92 | PDE4B (0.37) | SMN1; SMN2HPGDMRGPRX4PDE4BCYP2C19 | |
| SCHEMBL9750878 | 0.73 | PTPN7 (0.52) | PTGDR2SMN1; SMN2THRBMRGPRX4THRA | |
| SCHEMBL11183469 | 0.72 | THRB (0.52) | PTGDR2SMN1; SMN2THRBTHRAKDM4E | |
| SCHEMBL11439204 | 0.72 | FFAR1 (0.55) | PTGDR2MRGPRX4CYP2C19FFAR1 | |
| SCHEMBL8986399 | 0.70 | PTGDR2 (0.45) | PTGDR2SMN1; SMN2HPGDMRGPRX4CYP2C19 | |
| SCHEMBL10698024 | 0.69 | THRB (0.38) | SMN1; SMN2THRBTHRACYP2C9FFAR1 | |
| SCHEMBL4594851 | 0.69 | PTGDR2 (0.65) | PTGDR2 | |
| SCHEMBL10698183 | 0.68 | KMT2A (0.37) | SMN1; SMN2THRBHPGDCYP2C19CYP1A2 | |
| SCHEMBL11447794 | 0.68 | PPARA (0.43) | THRBMRGPRX4CYP2C19CYP1A2 | |
| SCHEMBL9750971 | 0.67 | PTPN7 (0.48) | PTGDR2SMN1; SMN2THRBMRGPRX4THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272533-A2 | Substituted phenoxypyridines | BAYER AG (DE) | 1988-06-29 | — | — | EP | disclosed |