Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KIF20B | Q96Q89 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10697700 | 0.81 | TDP1 (0.47) | KMT2ACYP1A2CYP2C19NPSR1HPGD | |
| SCHEMBL27260206 | 0.76 | PDE2A (0.38) | KMT2ACYP1A2CYP2C19KDM4EHPGD | |
| SCHEMBL10696996 | 0.73 | KMT2A (0.46) | KMT2ACYP1A2CYP2C19KDM4ELMNA | |
| SCHEMBL10698683 | 0.73 | TDP1 (0.44) | KMT2ACYP1A2CYP2C19NPSR1HPGD | |
| SCHEMBL10695727 | 0.70 | TDP1 (0.42) | KMT2ACYP1A2CYP2C19NPSR1HPGD | |
| SCHEMBL10697029 | 0.70 | TDP1 (0.42) | KMT2ANPSR1HPGDCYP3A4TSHR | |
| SCHEMBL10538432 | 0.69 | RAB9A (0.49) | CYP1A2CYP2C19NPSR1HPGDCYP3A4 | |
| SCHEMBL10696580 | 0.69 | MAPT (0.63) | KMT2ALMNANPSR1HPGDCYP3A4 | |
| SCHEMBL1531076 | 0.69 | DHODH (0.39) | LMNAKDRMAPK14TNNI3KSMN1; SMN2 | |
| SCHEMBL20476784 | 0.68 | TXNRD1 (0.57) | NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272533-A2 | Substituted phenoxypyridines | BAYER AG (DE) | 1988-06-29 | — | — | EP | disclosed |