Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | PPOX | P50336 | 1/20 | 0.38 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10696732 | 0.90 | TXNRD1 (0.39) | THRBMEN1KMT2ATDP1TTR | |
| SCHEMBL20471458 | 0.76 | TXNRD1 (0.39) | THRBMEN1KMT2ATDP1TTR | |
| SCHEMBL20471446 | 0.76 | TXNRD1 (0.50) | TXNRD1MAPTHTT | |
| SCHEMBL10697964 | 0.71 | KDM4E (0.40) | THRBMEN1KMT2ATDP1TTR | |
| SCHEMBL10699015 | 0.71 | TDP1 (0.42) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10698723 | 0.69 | PTGDR2 (0.41) | THRBTHRAKDM4EHTTFFAR1 | |
| SCHEMBL2698697 | 0.68 | MEN1 (0.57) | MEN1KMT2AHTTPPARD | |
| SCHEMBL10697439 | 0.68 | MEN1 (0.38) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10697700 | 0.67 | TDP1 (0.47) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL20278129 | 0.67 | CTSB (0.44) | MEN1KMT2AMAPTKDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272533-A2 | Substituted phenoxypyridines | BAYER AG (DE) | 1988-06-29 | — | — | EP | disclosed |