Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4949768 | 0.81 | GPR84 (0.47) | GPR84MEN1KMT2AKCNH2ALDH1A1 | |
| SCHEMBL5814755 | 0.74 | MCL1 (0.36) | ALDH1A1 | |
| SCHEMBL3264269 | 0.69 | PI4KA (0.35) | GPR84MEN1KMT2ATSHRKCNH2 | |
| SCHEMBL10818337 | 0.68 | KMT2A (0.37) | GPR84MEN1KMT2AKCNH2ALDH1A1 | |
| SCHEMBL3662375 | 0.68 | DHFR (0.45) | MEN1KMT2AKCNH2ALDH1A1 | |
| SCHEMBL10815973 | 0.68 | MEN1 (0.37) | GPR84MEN1KMT2AKCNH2ALDH1A1 | |
| SCHEMBL10816555 | 0.68 | MEN1 (0.37) | GPR84MEN1KMT2AKCNH2ALDH1A1 | |
| SCHEMBL28117492 | 0.67 | TSHR (0.38) | MEN1KMT2ATSHRKCNH2ALDH1A1 | |
| SCHEMBL27640018 | 0.66 | GPR84 (0.38) | GPR84ALDH1A1 | |
| SCHEMBL3265562 | 0.66 | MEN1 (0.39) | MEN1KMT2ATSHRKCNH2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4749712-A | Antiinflammatory and/or analgesic 5-alkylthiophenes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-06-07 | — | — | US | disclosed |
| US-4318911-A | 5,6-Diaryl-1,2,4-triazines as topical antithrombotic agents | ELI LILLY AND COMPANY (US) | 1982-03-09 | — | — | US | disclosed |