Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 3/20 | 0.32 |
| ▸ | THRB | P10828 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11780808 | 0.77 | DHFR (0.43) | TLR8TLR7 | |
| SCHEMBL5447243 | 0.76 | NPSR1 (0.34) | ALDH1A1NPSR1HPGD | |
| SCHEMBL5138373 | 0.74 | KCNH2 (0.43) | TSHRKCNH2GCGRALDH1A1PKM | |
| SCHEMBL17008157 | 0.71 | TSHR (0.57) | TSHRCYP19A1KCNH2ALDH1A1THRB | |
| SCHEMBL8636988 | 0.70 | GAA (0.33) | TSHRALDH1A1NPSR1TLR8TLR7 | |
| SCHEMBL2484848 | 0.69 | ALDH1A1 (0.35) | TSHRKCNH2ALDH1A1PKMHPGD | |
| SCHEMBL5814755 | 0.69 | MCL1 (0.36) | MCL1ALDH1A1NPSR1TLR8TLR7 | |
| SCHEMBL5679424 | 0.68 | TSHR (0.50) | TSHRCYP19A1KCNH2ALDH1A1NPSR1 | |
| SCHEMBL460363 | 0.68 | IMPDH2 (0.41) | TSHRCYP19A1GCGRNPSR1THRA | |
| SCHEMBL11667176 | 0.68 | CYP19A1 (0.50) | TSHRCYP19A1ALDH1A1NPSR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101056675-B | Delayed foaming dental mousse and method of using same | 高露洁-棕榄公司 | 2016-12-28 | — | — | CN | disclosed |