Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1506320 | 0.75 | POLB (0.39) | POLB | |
| SCHEMBL428508 | 0.74 | GBA1 (0.50) | SIGMAR1 | |
| SCHEMBL31546127 | 0.74 | POLB (0.38) | POLBTSHRTP53DAONAAA | |
| SCHEMBL9359971 | 0.73 | ADRA2A (0.41) | TSHRTP53SIGMAR1KCNH2ADRA2A | |
| SCHEMBL4247865 | 0.73 | GBA1 (0.59) | ADRA2AADRA2BADRA2CADRA1DHTR1D | |
| SCHEMBL13008930 | 0.73 | S1PR4 (0.45) | HDAC6KDM1A | |
| SCHEMBL13165310 | 0.71 | SIGMAR1 (0.48) | SIGMAR1KCNH2 | |
| Hydrochloric Acid SCHEMBL7400329 | 0.71 | GBA1 (0.58) | ADRA2AADRA2BADRA2CADRA1DHTR1D | |
| SCHEMBL10697151 | 0.71 | METAP2 (0.40) | POLBTSHRTP53METAP2DAO | |
| SCHEMBL11629119 | 0.71 | GLA (0.59) | POLBTSHRTP53DAONAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0259977-A2 | Tertiary amine compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-03-16 | — | — | EP | disclosed |