Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | ALPL | P05186 | 1/20 | 0.51 |
| ▸ | ALPI | P09923 | 1/20 | 0.51 |
| ▸ | ALPG | P10696 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | F2R | P25116 | 1/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9539183 | 0.89 | MMP2 (0.53) | ALDH1A1LMNANPSR1KMT2ANPC1 | |
| SCHEMBL1307623 | 0.82 | ALDH1A1 (0.55) | ALDH1A1LMNARECQLNPSR1ALPL | |
| SCHEMBL2400105 | 0.81 | SIGMAR1 (0.45) | SYKIRAK4MMP2MMP9CA12 | |
| SCHEMBL17017323 | 0.79 | HCRTR1 (0.55) | ALDH1A1KMT2ANPC1IRAK4CYP1A2 | |
| SCHEMBL4116189 | 0.78 | HDAC4 (0.52) | NPSR1NPC1MMP2MMP9CA12 | |
| SCHEMBL9701078 | 0.78 | HDAC4 (0.52) | NPSR1NPC1MMP2MMP9CA12 | |
| SCHEMBL4711538 | 0.78 | HDAC4 (0.52) | NPSR1NPC1MMP2MMP9CA12 | |
| SCHEMBL4760506 | 0.78 | HDAC4 (0.52) | NPSR1NPC1MMP2MMP9CA12 | |
| SCHEMBL3456445 | 0.78 | ALDH1A1 (0.73) | ALDH1A1LMNANPSR1ALPLALPI | |
| Hydrochloric Acid SCHEMBL17007131 | 0.78 | HCRTR1 (0.54) | ALDH1A1KMT2ANPC1IRAK4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263208-A2 | Antiarrhythmic use of aminocycloalkylamides | THE UPJOHN COMPANY (US) | 1988-04-13 | — | — | EP | disclosed |
| EP-0224566-A1 | ANTIARRHYTHMIC USE FOR AMINOCYCLOALKYLAMIDES | THE UPJOHN COMPANY (US) | 1987-06-10 | — | — | EP | disclosed |
| WO-1986007257-A2 | ANTIARRHYTHMIC USE FOR AMINOCYCLOALKYLAMIDES | THE UPJOHN COMPANY (US) | 1986-12-18 | — | — | WO | disclosed |