Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 4/20 | 0.32 |
| ▸ | NOS1 | P29475 | 4/20 | 0.32 |
| ▸ | NOS2 | P35228 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10702646 | 0.89 | SCN2A (0.34) | NOS1NOS2 | |
| SCHEMBL789308 | 0.88 | — | — | |
| SCHEMBL3715413 | 0.87 | SCN2A (0.36) | NOS1NOS2 | |
| SCHEMBL2919395 | 0.83 | — | — | |
| SCHEMBL947266 | 0.80 | NOS3 (0.32) | NOS3NOS1NOS2 | |
| SCHEMBL2915584 | 0.80 | — | — | |
| SCHEMBL2916542 | 0.79 | SIGMAR1 (0.31) | — | |
| SCHEMBL2920801 | 0.79 | SIGMAR1 (0.31) | — | |
| SCHEMBL2918112 | 0.79 | — | — | |
| SCHEMBL947605 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0287951-A2 | 7-Piperazinyl- or 7-Morpholino-4-oxo-quinoline-3-carboxylic acid derivatives, their preparation and their use as antimicrobial agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-10-26 | — | — | EP | disclosed |