Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN2A | Q99250 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 4/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.33 |
| ▸ | GUSB | P08236 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.32 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.32 |
| ▸ | GLB1 | P16278 | 1/20 | 0.31 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10702646 | 0.98 | SCN2A (0.34) | SCN2AALDH1A1GBA1SPHK1GUSB | |
| SCHEMBL3254586 | 0.89 | ALDH1A1 (0.36) | SCN2AALDH1A1GBA1SPHK1GUSB | |
| SCHEMBL254648 | 0.87 | GBA1 (0.33) | SCN2AALDH1A1GBA1SPHK1GUSB | |
| SCHEMBL10700174 | 0.87 | NOS3 (0.32) | NOS1NOS2 | |
| SCHEMBL789435 | 0.81 | NOS1 (0.35) | GLB1NOS1NOS2 | |
| SCHEMBL948381 | 0.80 | SIGMAR1 (0.34) | — | |
| SCHEMBL2919395 | 0.79 | — | — | |
| SCHEMBL10701436 | 0.78 | SPHK2 (0.35) | ALDH1A1GBA1SPHK1EPHX1NOS1 | |
| SCHEMBL947605 | 0.78 | — | — | |
| SCHEMBL10707537 | 0.77 | EPHX1 (0.41) | SCN2AALDH1A1EPHX1NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010137738-A1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF STRESS-RELATED CONDITIONS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2010-12-02 | — | — | WO | disclosed |