Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12706342 | 0.83 | TDP1 (0.69) | TDP1MAPK1GAAALDH1A1LMNA | |
| SCHEMBL19159686 | 0.83 | CHRM2 (0.62) | CHRM2TDP1MAPK1ALDH1A1LMNA | |
| SCHEMBL4815797 | 0.78 | MAPK1 (0.57) | CHRM2TDP1MAPK1GAAALDH1A1 | |
| SCHEMBL4815807 | 0.78 | MAPK1 (0.57) | CHRM2TDP1MAPK1GAAALDH1A1 | |
| SCHEMBL5433598 | 0.77 | CHRM2 (0.58) | CHRM2TDP1MAPK1GAAALDH1A1 | |
| SCHEMBL5446400 | 0.77 | CHRM2 (0.65) | CHRM2MAPK1ALDH1A1LMNAPKM | |
| SCHEMBL9763711 | 0.77 | PKM (0.74) | TDP1MAPK1ALDH1A1LMNAPKM | |
| SCHEMBL15058202 | 0.76 | POLB (0.60) | CHRM2TDP1MAPK1ALDH1A1LMNA | |
| SCHEMBL29995115 | 0.76 | POLB (0.60) | CHRM2TDP1MAPK1ALDH1A1LMNA | |
| SCHEMBL21800486 | 0.76 | CHRM2 (0.59) | CHRM2TDP1MAPK1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273659-A1 | Azaspiro compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1988-07-06 | — | — | EP | disclosed |