SCHEMBL1067253

SCHEMBL1067253

OCCc1ccccc1Oc1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 1/20 0.67
SLC6A4 P31645 4/20 0.55
SLC6A2 P23975 2/20 0.55
RIPK1 Q13546 1/20 0.55
FFAR1 O14842 1/20 0.48
CYP19A1 P11511 1/20 0.45
TTR P02766 1/20 0.44
LTA4H P09960 2/20 0.44
PPARA Q07869 1/20 0.43
FFAR4 Q5NUL3 1/20 0.43
CTNNB1 P35222 1/20 0.43
HTR2A P28223 2/20 0.42
TSHR P16473 1/20 0.42
SLC6A3 Q01959 1/20 0.42
ALDH1A1 P00352 2/20 0.42
RECQL P46063 1/20 0.42
HPGD P15428 1/20 0.42
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1070099 0.89 HRH1 (0.62) HRH1SLC6A4SLC6A2RIPK1FFAR1
SCHEMBL6236000 0.87 HRH1 (0.48) HRH1SLC6A4SLC6A2RIPK1SLC6A3
Acrylic Acid SCHEMBL1484166 0.87 HRH1 (0.53) HRH1SLC6A4SLC6A2RIPK1FFAR1
SCHEMBL28326055 0.85 SLC6A4 (0.61) HRH1SLC6A4SLC6A2RIPK1HTR2A
SCHEMBL8516631 0.85 HRH1 (0.59) HRH1SLC6A4SLC6A2RIPK1FFAR1
SCHEMBL194417 0.83 HRH1 (0.60) HRH1SLC6A4SLC6A2RIPK1FFAR1
SCHEMBL2061850 0.83 HRH1 (0.56) HRH1SLC6A4SLC6A2RIPK1FFAR1
SCHEMBL11100370 0.82 HRH1 (0.44) HRH1SLC6A4SLC6A2RIPK1SLC6A3
SCHEMBL10874841 0.81 MAOB (0.51) HRH1SLC6A4SLC6A2RIPK1SLC6A3
SCHEMBL5545669 0.80 HRH1 (0.67) HRH1SLC6A4SLC6A2RIPK1FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116693581-B Method for depolymerizing lignin by visible light catalysis 深圳中农秸美科技股份有限公司 2024-06-18 CN claimed
CN-117582997-A Preparation method and application of ruthenium metal loaded nickel aluminate spinel catalyst 复旦大学 2024-02-23 CN claimed
CN-117304016-A Catalytic oxidation cracking method for aromatic ether substances 郑州大学 2023-12-29 CN claimed
CN-117085736-A perovskite/CTF composite photocatalyst and preparation method and application thereof 齐鲁工业大学(山东省科学院) 2023-11-21 CN claimed
CN-116693581-A Method for depolymerizing lignin by visible light catalysis 深圳中农秸美科技股份有限公司 2023-09-05 CN claimed
CN-116410062-A Method for catalyzing oxidative depolymerization of lignin 四川农业大学 2023-07-11 CN claimed
CN-118291999-A Phosphorus-doped copper oxide composite electrocatalyst and preparation method and application thereof 齐鲁工业大学(山东省科学院) 2024-07-05 CN disclosed
CN-116693581-B Method for depolymerizing lignin by visible light catalysis 深圳中农秸美科技股份有限公司 2024-06-18 CN disclosed
CN-118142522-A Preparation method of metal oxide/ruthenium-tungsten composite catalyst and application of catalyst in catalyzing C-O bond cracking in lignin 内蒙古工业大学 2024-06-07 CN disclosed
CN-118122344-A Metal oxide@indium zinc sulfide photoelectric catalyst and preparation method and application thereof 东北林业大学 2024-06-04 CN disclosed
CN-116689008-B Transition metal doping defective g-C for lignin depolymerization3N4Photocatalytic material and preparation method thereof 深圳中农秸美科技股份有限公司 2024-05-28 CN disclosed
CN-117943084-A Transition metal catalyst, preparation method and method for preparing organic acid by oxidation and pyrolysis of secondary alcohol 中国科学院大连化学物理研究所 2024-04-30 CN disclosed
CN-117582997-A Preparation method and application of ruthenium metal loaded nickel aluminate spinel catalyst 复旦大学 2024-02-23 CN disclosed
WO-2011003029-A2 CATALYTIC DISPROPORTIONATION AND CATALYTIC REDUCTION OF CARBON-CARBON AND CARBON-OXYGEN BONDS OF LIGNIN AND OTHER ORGANIC SUBSTRATES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2011-01-06 WO disclosed
US-20100130559-A1 NOVEL PHENYL-ISOXAZOL-3-OL DERIVATIVE BANYU PHARMACEUTICAL CO., LTD. (JP) 2010-05-27 US disclosed
EP-2098517-A1 NOVEL PHENYL-ISOXAZOL-3-OL DERIVATIVE BANYU PHARMACEUTICAL CO., LTD. (JP) 2009-09-09 EP disclosed
WO-2002004411-A1 METHODS FOR PROTECTION OF STRATIFIED SQUAMOUS EPITHELIUM AGAINST INJURY BY NOXIOUS SUBSTANCES AND NOVEL AGENTS FOR USE THEREFOR THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) 2002-01-17 WO disclosed
US-4870180-A 1,2-dihydro-4-methyl-1-oxo-5H-pyrido(4,3-b)indoles and the process for their synthesis SANOFI AND CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 1989-09-26 US disclosed
EP-0238411-A1 1,2-Dihydro-4-methyl-1-oxo-5H-pyrido(4,3-b) indoles and their preparation SANOFI (FR) 1987-09-23 EP disclosed
US-4255152-A USING A DISPERSE DYE, WATER, AND AN ADDUCT OF ETHYLENE, PROPYLENE, OR STYRENE OXIDE AND A CYCLIC-SUBSTITUTED PHENOL; LEVELLING CIBA-GEIGY CORPORATION (US) 1981-03-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100130559-A1 NOVEL PHENYL-ISOXAZOL-3-OL DERIVATIVE GPR119, FFAR3, FFAR2 HRH1 731/4885SLC6A4 1487/4885SLC6A2 1811/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.