Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 17/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 15/20 | 0.55 |
| ▸ | CHRNB4 | P30926 | 6/20 | 0.55 |
| ▸ | CHRNA3 | P32297 | 6/20 | 0.55 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.55 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.55 |
| ▸ | CHRNA1 | P02708 | 4/20 | 0.55 |
| ▸ | CHRNG | P07510 | 4/20 | 0.55 |
| ▸ | CHRNB1 | P11230 | 4/20 | 0.55 |
| ▸ | CHRND | Q07001 | 4/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9360364 | 0.98 | SLC6A3 (0.60) | SLC6A3KDM4EALDH1A1GAASLC6A2 | |
| Hydrochloric Acid SCHEMBL9596538 | 0.98 | SLC6A3 (0.60) | SLC6A3KDM4EALDH1A1GAASLC6A2 | |
| SCHEMBL9796926 | 0.98 | SLC6A3 (0.60) | SLC6A3KDM4EALDH1A1GAASLC6A2 | |
| Hydrochloric Acid SCHEMBL9796810 | 0.97 | SLC6A3 (0.58) | SLC6A3KDM4EALDH1A1GAASLC6A2 | |
| Hydrochloric Acid SCHEMBL9797234 | 0.97 | SLC6A3 (0.58) | SLC6A3KDM4EALDH1A1GAASLC6A2 | |
| SCHEMBL9597221 | 0.87 | SLC6A3 (0.48) | SLC6A3KDM4EALDH1A1GAASLC6A2 | |
| SCHEMBL10701944 | 0.85 | MEN1 (0.48) | SLC6A3KDM4EALDH1A1GAASLC6A2 | |
| SCHEMBL10469275 | 0.85 | HRH3 (0.49) | SLC6A3KDM4EALDH1A1GAASLC6A2 | |
| SCHEMBL17644179 | 0.84 | SLC6A3 (0.65) | SLC6A3KDM4EALDH1A1GAASLC6A2 | |
| SCHEMBL895863 | 0.84 | SLC6A3 (0.65) | SLC6A3KDM4EALDH1A1GAASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5236922-A | Method for treating depression using 1-(aminophenyl)-2-aminopropanone derivatives | LABORATOIRE L. LAFON (FR) | 1993-08-17 | — | — | US | claimed |
| EP-0174242-B1 | 1-(AMINO-PHENYL)-2-AMINO PROPANON DERIVATIVES, THEIR USE IN THERAPY AND PROCESS FOR THEIR PREPARATION | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1988-01-13 | — | — | EP | claimed |
| EP-0174242-A2 | 1-(Amino-phenyl)-2-amino propanon derivatives, their use in therapy and process for their preparation | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1986-03-12 | — | — | EP | claimed |
| EP-0174242-B1 | 1-(AMINO-PHENYL)-2-AMINO PROPANON DERIVATIVES, THEIR USE IN THERAPY AND PROCESS FOR THEIR PREPARATION | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1988-01-13 | — | — | EP | disclosed |
| EP-0174242-A2 | 1-(Amino-phenyl)-2-amino propanon derivatives, their use in therapy and process for their preparation | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1986-03-12 | — | — | EP | disclosed |