Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | ATP4A | P20648 | 1/20 | 0.31 |
| ▸ | ATP4B | P51164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10699725 | 0.90 | ATP4A (0.33) | MAPTPOLBATP4AATP4B | |
| SCHEMBL9678434 | 0.87 | PDE10A (0.39) | PDE10AF10AMY1APOLBATP4A | |
| SCHEMBL10699957 | 0.87 | LMNA (0.37) | PDE10AF10 | |
| SCHEMBL6481794 | 0.86 | ATP4A (0.45) | MAPTPOLBTP53ATP4AATP4B | |
| SCHEMBL6481789 | 0.86 | ATP4A (0.36) | MAPTPOLBATP4AATP4B | |
| SCHEMBL7930040 | 0.85 | ATP4A (0.42) | ALOX5EPHX2PDE10AF10HCRTR1 | |
| SCHEMBL9398067 | 0.82 | ATP4A (0.42) | MAPTPOLBTP53ATP4AATP4B | |
| SCHEMBL10701638 | 0.81 | MAOB (0.32) | MAPTPOLBTP53ATP4AATP4B | |
| SCHEMBL10699863 | 0.81 | CRHR1 (0.33) | ALOX5EPHX2HCRTR1HCRTR2 | |
| SCHEMBL10700467 | 0.80 | PDE10A (0.36) | PDE10AF10ATP4AATP4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251536-A1 | Benzimidazoles, their production, formulation and use as gastric acid secretion inhibitors | FISONS plc (GB) | 1988-01-07 | — | — | EP | claimed |