Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 2/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3692343 | 0.86 | NQO2 (0.35) | — | |
| SCHEMBL10701972 | 0.81 | ALOX5 (0.37) | HCRTR1HCRTR2ALOX5EPHX2 | |
| SCHEMBL9576670 | 0.77 | NQO2 (0.34) | — | |
| SCHEMBL10700537 | 0.76 | PTGS2 (0.39) | CRHR1 | |
| SCHEMBL10700191 | 0.76 | IGF1R (0.32) | — | |
| SCHEMBL6481794 | 0.76 | ATP4A (0.45) | ACHE | |
| SCHEMBL6481789 | 0.76 | ATP4A (0.36) | CRHR1 | |
| SCHEMBL9398067 | 0.73 | ATP4A (0.42) | — | |
| SCHEMBL10701999 | 0.73 | OGT (0.34) | — | |
| SCHEMBL10699725 | 0.73 | ATP4A (0.33) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251536-A1 | Benzimidazoles, their production, formulation and use as gastric acid secretion inhibitors | FISONS plc (GB) | 1988-01-07 | — | — | EP | claimed |
| EP-0251536-A1 | Benzimidazoles, their production, formulation and use as gastric acid secretion inhibitors | FISONS plc (GB) | 1988-01-07 | — | — | EP | disclosed |