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Tetramethrin

Tetramethrin

SCHEMBL1070227

CC(C)=CC1C(C(=O)OCN2C(=O)C3=C(CCCC3)C2=O)C1(C)C.CCOP(=S)(OCC)SC(CCl)N1C(=O)c2ccccc2C1=O.COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O.c1cn[nH]c1

nearest known ligand 0.34

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Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ PLIN1 O60240 1/20 0.34
▸ ALDH1A1 P00352 1/20 0.34
▸ MAPT P10636 1/20 0.34
▸ HPGD P15428 1/20 0.34
▸ ALOX15 P16050 1/20 0.34
▸ PLIN5 Q00G26 1/20 0.34
▸ ABHD5 Q8WTS1 1/20 0.34
▸ LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetramethrin SCHEMBL1276528 0.94 PLIN1 (0.39) PLIN1ALDH1A1MAPTHPGDALOX15
Phosmet SCHEMBL1070798 0.81 ALDH1A1 (0.53) PLIN1ALDH1A1MAPTHPGDALOX15
Tetramethrin SCHEMBL4422842 0.77 LMNA (0.46) LMNA
Phosmet SCHEMBL1070968 0.74 ALDH1A1 (0.63) PLIN1ALDH1A1MAPTHPGDALOX15
Tetramethrin SCHEMBL7178768 0.69 CYP3A4 (0.48) ALDH1A1ALOX15LMNA
Tetramethrin SCHEMBL7926801 0.68 LMNA (0.56) LMNA
Tetramethrin SCHEMBL27009 0.68 LMNA (0.56) LMNA
(1R)-Trans-Tetramethrin SCHEMBL2973441 0.68 LMNA (0.56) LMNA
Tetramethrin SCHEMBL22714265 0.68 LMNA (0.56) LMNA
Tetramethrin SCHEMBL7173264 0.66 TDP1 (0.46) ALDH1A1MAPTALOX15LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2268138-A2 SILICON DIOXIDE DISPERSION Evonik Degussa GmbH (DE) 2011-01-05 — — EP disclosed
WO-2009095141-A2 SILICON DIOXIDE DISPERSION EVONIK DEGUSSA GMBH (DE) 2009-08-06 — — WO disclosed
EP-1960485-A4 COMPOSITION AND PROCESS FOR COLORING WOOD OSMOSE INC (US) 2009-07-08 — — EP disclosed
EP-1960485-A2 COMPOSITION AND PROCESS FOR COLORING WOOD Osmose, Inc. (US) 2008-08-27 — — EP disclosed
WO-2007070769-A2 COMPOSITION AND PROCESS FOR COLORING WOOD OSMOSE, INC. (US) 2007-06-21 — — WO disclosed