Phosmet

Phosmet

SCHEMBL1070968

CCOP(=S)(OCC)SC(CCl)N1C(=O)c2ccccc2C1=O.COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.63
MAPT P10636 3/20 0.63
HPGD P15428 3/20 0.63
ALOX15 P16050 2/20 0.63
PLIN1 O60240 1/20 0.63
PLIN5 Q00G26 1/20 0.63
ABHD5 Q8WTS1 1/20 0.63
LMNA P02545 2/20 0.35
CYP3A4 P08684 2/20 0.35
HSD17B10 Q99714 2/20 0.35
KDM4E B2RXH2 1/20 0.35
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosmet SCHEMBL1070798 0.91 ALDH1A1 (0.53) ALDH1A1MAPTHPGDALOX15PLIN1
SCHEMBL29424499 0.88 PLIN1 (0.41) ALDH1A1MAPTHPGDALOX15PLIN1
SCHEMBL122099 0.88 PLIN1 (0.41) ALDH1A1MAPTHPGDALOX15PLIN1
SCHEMBL3728876 0.88 PLIN1 (0.41) ALDH1A1MAPTHPGDALOX15PLIN1
Dimethyl Sulfone SCHEMBL19032723 0.84 ALDH1A1 (0.38) ALDH1A1MAPTHPGDALOX15PLIN1
SCHEMBL13596981 0.83 ALDH1A1 (0.81) ALDH1A1MAPTHPGDALOX15PLIN1
Phosmet SCHEMBL1663406 0.80 ALDH1A1 (1.00) ALDH1A1MAPTHPGDALOX15PLIN1
Phosmet SCHEMBL29350557 0.80 ALDH1A1 (1.00) ALDH1A1MAPTHPGDALOX15PLIN1
Phosmet SCHEMBL3620 0.80 ALDH1A1 (1.00) ALDH1A1MAPTHPGDALOX15PLIN1
Tetramethrin SCHEMBL1276528 0.78 PLIN1 (0.39) ALDH1A1MAPTHPGDALOX15PLIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2285741-A2 SILICA DISPERSION Evonik Degussa GmbH (DE) 2011-02-23 EP disclosed
EP-2268138-A2 SILICON DIOXIDE DISPERSION Evonik Degussa GmbH (DE) 2011-01-05 EP disclosed
WO-2009095141-A2 SILICON DIOXIDE DISPERSION EVONIK DEGUSSA GMBH (DE) 2009-08-06 WO disclosed
WO-2009095139-A2 SILICA DISPERSION EVONIK DEGUSSA GMBH (DE) 2009-08-06 WO disclosed
EP-1765072-A1 USE OF PHOSPHATED ALCANOLS AS DISPERSANTS, EMULSIFIERS, HYDROTROPES, WETTING AGENTS AND COMPATABILITY AGENTS IN AGRICULTURAL COMPOSITIONS Akzo Nobel N.V. (NL) 2007-03-28 EP disclosed
WO-2006019772-A1 USE OF PHOSPHATED ALCANOLS AS DISPERSANTS, EMULSIFIERS, HYDROTROPES, WETTING AGENTS AND COMPATABILITY AGENTS IN AGRICULTURAL COMPOSITIONS AKZO NOBEL N.V. (NL) 2006-02-23 WO disclosed