Gluconic Acid

Gluconic Acid

SCHEMBL1070308

NCC(=O)O.O=C(O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.[Zn]

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9A

The experimentally established mechanism targets of Gluconic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.76
LMNA P02545 3/20 0.53
USP2 O75604 1/20 0.53
SLCO1B1 Q9Y6L6 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.44
TDP1 Q9NUW8 1/20 0.42
TSHR P16473 2/20 0.42
CYP2C9 P11712 1/20 0.42
OR51E2 Q9H255 2/20 0.40
GLRA1 P23415 1/20 0.40
SLC6A9 P48067 1/20 0.40
KDM4E B2RXH2 2/20 0.33
GABRR1 P24046 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Gluconic Acid SCHEMBL29379109 1.00 PDE4A (0.76) PDE4ALMNAUSP2SLCO1B1L3MBTL1
Gluconic Acid SCHEMBL5805996 0.98 PDE4A (0.79) PDE4ALMNAUSP2SLCO1B1L3MBTL1
Gluconic Acid SCHEMBL28069153 0.98 PDE4A (0.79) PDE4ALMNAUSP2SLCO1B1L3MBTL1
Gluconic Acid SCHEMBL17965938 0.96 PDE4A (0.76) PDE4ALMNAUSP2SLCO1B1L3MBTL1
Gluconic Acid SCHEMBL25413097 0.89 PDE4A (0.95) PDE4ALMNAUSP2SLCO1B1L3MBTL1
Gluconic Acid SCHEMBL29367310 0.89 PDE4A (0.95) PDE4ALMNAUSP2SLCO1B1L3MBTL1
Gluconic Acid SCHEMBL29448461 0.89 PDE4A (0.95) PDE4ALMNAUSP2SLCO1B1L3MBTL1
Gluconic Acid SCHEMBL15703361 0.89 PDE4A (0.95) PDE4ALMNAUSP2SLCO1B1L3MBTL1
Gluconic Acid SCHEMBL6535948 0.89 PDE4A (0.95) PDE4ALMNAUSP2SLCO1B1L3MBTL1
Gluconic Acid SCHEMBL543242 0.89 PDE4A (0.95) PDE4ALMNAUSP2SLCO1B1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080075674-A1 chewable tablets having flavors and antitussive agents selected from dextromethorphan, noscapine, ethyl morphine, codeine, menthol, zinc gluconate glycine, and pectin; sustained release of flavors DUPRATT BRIAN D 2008-03-27 US claimed
US-20230241165-A1 MANNOSE-BINDING LECTIN FOR TREATMENT OR PROPHYLAXIS OF INFECTIOUS DISEASES ESS HOLDING GMBH (AT) 2023-08-03 US disclosed
EP-4146245-A1 MANNOSE-BINDING LECTIN FOR TREATMENT OR PROPHYLAXIS OF INFECTIOUS DISEASES ESS Holding GmbH (AT) 2023-03-15 EP disclosed
WO-2021222965-A1 MANNOSE-BINDING LECTIN FOR TREATMENT OR PROPHYLAXIS OF INFECTIOUS DISEASES ESS HOLDING GMBH (AT) 2021-11-11 WO disclosed
US-20170087056-A1 Blister Cards Promoting Intuitive Dosing PROCTER & GAMBLE (US) 2017-03-30 US disclosed
US-9526673-B2 Blister cards promoting intuitive dosing THE PROCTER & GAMBLE COMPANY (US) 2016-12-27 US disclosed
US-9445970-B2 Blister cards promoting intuitive dosing THE PROCTER & GAMBLE COMPANY (US) 2016-09-20 US disclosed
US-20160193112-A1 Blister Cards Promoting Intuitive Dosing PROCTER & GAMBLE (US) 2016-07-07 US disclosed
US-9314402-B2 Blister cards promoting intuitive dosing THE PROCTER & GAMBLE COMPANY (US) 2016-04-19 US disclosed
EP-2651365-B1 BLISTER CARDS PROMOTING INTUITIVE DOSING PROCTER & GAMBLE (US) 2016-02-24 EP disclosed
US-20060068038-A1 Mineral additives for improved processing of compositions containing vitamin E and saw palmetto PROETHIC LABORATORIES, L.L.C. (US) 2006-03-30 US disclosed
US-20050191369-A1 Compositions comprising vitamin E and saw palmetto PROETHIC LABORATORIES, L.L.C. (US) 2005-09-01 US disclosed
US-20030175332-A1 Methods of preventing or treating diseases and conditions using complex carbohydrates DERMAL RESEARCH LABORATORIES, INC. 2003-09-18 US disclosed
EP-1311276-A1 METHODS OF PREVENTING OR TREATING DISEASES AND CONDITIONS USING COMPLEX CARBOHYDRATES Dermal Research Laboratories, Inc. (US) 2003-05-21 EP disclosed
EP-0987021-B1 Slow release compositions containing a zinc compound and vitamin C derivatives GODFREY JOHN C (US) 2003-04-09 EP disclosed
WO-2002009728-A1 METHODS OF PREVENTING OR TREATING DISEASES AND CONDITIONS USING COMPLEX CARBOHYDRATES DERMAL RESEARCH LABORATORIES, INC. (US) 2002-02-07 WO disclosed
EP-1165097-A2 A PHARMACEUTICAL COMPOSITION OF COMPLEX CARBOHYDRATES AND ESSENTIAL OILS AND METHODS OF USING THE SAME Dermal Research Laboratories, Inc. (US) 2002-01-02 EP disclosed
US-6316008-B1 Combination of zinc ions and vitamin C and method of making GODFREY JOHN C (US) 2001-11-13 US disclosed
WO-2000044367-A2 A PHARMACEUTICAL COMPOSITION OF COMPLEX CARBOHYDRATES AND ESSENTIAL OILS AND METHODS OF USING THE SAME DERMAL RESEARCH LABORATORIES, INC. (US) 2000-08-03 WO disclosed
EP-0987021-A1 Slow release compositions containing a zinc compound and vitamin C derivatives Godfrey, John C. (US) 2000-03-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050191369-A1 Compositions comprising vitamin E and saw palmetto TTPA, GPX4, CYP24A1 PDE4A 4317/4885LMNA 1142/4885USP2 1775/4885
US-20060068038-A1 Mineral additives for improved processing of compositions containing vitamin E and saw palmetto SOST, TTPA, CYP24A1 PDE4A 4066/4885LMNA 1208/4885USP2 3050/4885
US-20230241165-A1 MANNOSE-BINDING LECTIN FOR TREATMENT OR PROPHYLAXIS OF INFECTIOUS DISEASES MASP2, MANBA, MAN2A1 PDE4A 4623/4885LMNA 465/4885USP2 4094/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.