Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7935845 | 0.89 | — | — | |
| SCHEMBL10708320 | 0.81 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL13183103 | 0.79 | ADH1A (0.46) | CYP1A2 | |
| SCHEMBL3448201 | 0.76 | ADH1A (0.39) | CYP1A2 | |
| SCHEMBL13158946 | 0.74 | ADH1A (0.42) | ALDH1A1 | |
| SCHEMBL2087043 | 0.74 | SLC29A1 (0.32) | — | |
| SCHEMBL6567107 | 0.70 | LTA4H (0.39) | CYP1A2CYP2D6LTA4HALDH1A1 | |
| SCHEMBL6333592 | 0.70 | MEN1 (0.36) | CYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL79285 | 0.70 | LTA4H (0.39) | CYP1A2CYP2D6LTA4HALDH1A1 | |
| SCHEMBL24951487 | 0.69 | DPP4 (0.35) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0124479-B1 | IMINOSULFON AMIDES AND PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL PREPARATIONS CONTAINING SUCH COMPOUNDS, AND THE COMPOUNDS FOR USE | CIBA-GEIGY AG (CH) | 1988-01-20 | — | — | EP | claimed |
| EP-0124479-A1 | Iminosulfon amides and processes for their preparation, pharmaceutical preparations containing such compounds, and the compounds for use | CIBA-GEIGY AG (CH) | 1984-11-07 | — | — | EP | claimed |
| EP-0124479-B1 | IMINOSULFON AMIDES AND PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL PREPARATIONS CONTAINING SUCH COMPOUNDS, AND THE COMPOUNDS FOR USE | CIBA-GEIGY AG (CH) | 1988-01-20 | — | — | EP | disclosed |
| US-4591597-A | FOR BLOOD SUGAR REDUCTION | CIBA-GEIGY CORPORATION (US) | 1986-05-27 | — | — | US | disclosed |
| EP-0124479-A1 | Iminosulfon amides and processes for their preparation, pharmaceutical preparations containing such compounds, and the compounds for use | CIBA-GEIGY AG (CH) | 1984-11-07 | — | — | EP | disclosed |