SCHEMBL1070355

SCHEMBL1070355

C=C(C(=O)O)C(CCOCC)(CCOCC)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.39
ALDH1A1 P00352 2/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1066223 0.86 THRB (0.35) THRBALDH1A1TSHR
SCHEMBL6515529 0.85 THRB (0.32) THRB
SCHEMBL6514986 0.85 THRB (0.41) THRBALDH1A1TSHR
SCHEMBL6513350 0.83 THRB (0.34) THRBALDH1A1TSHR
SCHEMBL6518671 0.82 HAO1 (0.30) THRB
SCHEMBL6523168 0.81 NAAA (0.34) THRBALDH1A1TSHR
SCHEMBL6515218 0.80 POLB (0.40) ALDH1A1TSHR
SCHEMBL6523751 0.79 KDM4E (0.34) ALDH1A1TSHR
SCHEMBL6525875 0.78 THRB (0.45) THRBALDH1A1TSHR
SCHEMBL6521050 0.78 NPC1 (0.36) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2186838-B1 METHOD FOR PRODUCING STAR POLYMER NIPPON SODA CO (JP) 2014-08-27 EP disclosed
EP-2275464-B1 Method for producing a polymer NIPPON SODA CO (JP) 2014-04-23 EP disclosed
US-8536280-B2 Star polymer and coupling agent for anionic polymerization TOHO CHEMICAL INDUSTRY CO., LTD. (JP) 2013-09-17 US disclosed
EP-1892255-B1 ACRYLIC ACID POLYMER NIPPON SODA CO (JP) 2012-08-01 EP disclosed
US-8067515-B2 Method of producing an acrylic acid-based polymer NIPPON SODA CO., LTD. (JP) 2011-11-29 US disclosed
US-20110046333-A1 ACRYLIC ACID-BASED POLYMER AND METHOD OF PRODUCING THE SAME NIPPON SODA CO., LTD. (JP) 2011-02-24 US disclosed
EP-2275464-A1 Method for producing a polymer NIPPON SODA CO., LTD. (JP) 2011-01-19 EP disclosed
US-7847045-B2 Acrylic acid-based polymer and method of producing the same NIPPON SODA CO., LTD. (JP) 2010-12-07 US disclosed
US-20100210805-A1 METHOD FOR PRODUCING STAR POLYMER NIPPON SODA CO., LTD. (JP) 2010-08-19 US disclosed
EP-2186838-A1 METHOD FOR PRODUCING STAR POLYMER Nippon Soda Co., Ltd. (JP) 2010-05-19 EP disclosed
US-20100056748-A1 Novel star polymer and coupling agent for anionic polymerization TOHO CHEMICAL INDUSTRY CO., LTD. (JP) 2010-03-04 US disclosed
US-20090111961-A1 Acrylic Acid-Based Polymer and Method of Producing the Same NIPPON SODA CO., LTD. (JP) 2009-04-30 US disclosed
US-7494759-B2 Positive resist compositions and process for the formation of resist patterns with the same TOKYO OHKA KOGYO CO., LTD. (JP) 2009-02-24 US disclosed
EP-1892255-A1 ACRYLIC ACID POLYMER AND METHOD FOR PRODUCING SAME NIPPON SODA CO., LTD. (JP) 2008-02-27 EP disclosed
US-20070224538-A1 Positive Resist Compositions and Process for the Formation of Resist Patterns With the Same TOKYO OHKA KOGYO CO., LTD. (JP) 2007-09-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100056748-A1 Novel star polymer and coupling agent for anionic polymerization MSN, PAM, STARD10 THRB 4497/4885ALDH1A1 4034/4885TSHR 3352/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.