SCHEMBL1070486

SCHEMBL1070486

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nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 1/20 0.38
GRIK2 Q13002 1/20 0.38
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29275514 0.84 GRIK1 (0.36) GRIK1GRIK2ALDH1A1
SCHEMBL11767085 0.83 GRIK1 (0.38) GRIK1GRIK2
SCHEMBL28383119 0.82 GLO1 (0.44) GRIK1GRIK2ALDH1A1
SCHEMBL7556438 0.82 GLO1 (0.44) GRIK1GRIK2ALDH1A1
SCHEMBL2946388 0.80 ALDH1A1 (0.41) ALDH1A1
SCHEMBL31542619 0.80 GLO1 (0.42) GRIK1GRIK2ALDH1A1
SCHEMBL5921557 0.80
SCHEMBL4423141 0.80
SCHEMBL16440995 0.80
Ammonia Solution, Strong SCHEMBL1021124 0.78 ALDH1A1 (0.35) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8475844-B2 Fluoropolymer-based medical implant coating compositions BOSTON SCIENTIFIC SCIMED, INC. (US) 2013-07-02 US disclosed
EP-2271708-A1 FLUOROPOLYMER-BASED MEDICAL IMPLANT COATING COMPOSITIONS Boston Scientific Scimed, Inc. (US) 2011-01-12 EP disclosed
WO-2009146194-A1 FLUOROPOLYMER-BASED MEDICAL IMPLANT COATING COMPOSITIONS BOSTON SCIENTIFIC SCIMED, INC. (US) 2009-12-03 WO disclosed
US-20090264539-A1 FLUOROPOLYMER-BASED MEDICAL IMPLANT COATING COMPOSITIONS BOSTON SCIENTIFIC SCIMED, INC. (US) 2009-10-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090264539-A1 FLUOROPOLYMER-BASED MEDICAL IMPLANT COATING COMPOSITIONS CAD, FIBP, FGF23 GRIK1 1887/4885GRIK2 1875/4885ALDH1A1 1881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.