Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4323999 | 0.77 | KMT2A (0.60) | KMT2AALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL17735706 | 0.74 | ALDH1A1 (0.56) | KMT2AALDH1A1SMN1; SMN2LMNATP53 | |
| SCHEMBL2545750 | 0.73 | HSPA5 (0.36) | KMT2AALDH1A1SMN1; SMN2LMNATP53 | |
| SCHEMBL8614764 | 0.70 | ALDH1A1 (0.44) | KMT2AALDH1A1SMN1; SMN2LMNATP53 | |
| SCHEMBL10723987 | 0.70 | HDAC1 (0.41) | KMT2AALDH1A1SMN1; SMN2LMNATP53 | |
| SCHEMBL11253016 | 0.70 | TP53 (0.45) | ALDH1A1SMN1; SMN2LMNATP53HTT | |
| SCHEMBL28593004 | 0.69 | KDM4E (0.38) | KMT2AALDH1A1LMNAHTTKDM4E | |
| SCHEMBL1461137 | 0.68 | ALDH1A1 (0.36) | KMT2AALDH1A1LMNAHTTKDM4E | |
| SCHEMBL27861510 | 0.68 | ALDH1A1 (0.61) | KMT2AALDH1A1SMN1; SMN2LMNATP53 | |
| SCHEMBL10061323 | 0.67 | PTGER1 (0.37) | KMT2AALDH1A1LMNATP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150440-B1 | ENAMEL MIXTURES BASED ON HYDANTOIN GROUP CONTAINING POLYMERS AND THEIR APPLICATION | BAYER AG (DE) | 1988-05-18 | — | — | EP | disclosed |
| EP-0112528-B1 | PROCESS FOR THE PRODUCTION OF HYDANTOIN ESTERS | BAYER AG (DE) | 1988-04-20 | — | — | EP | disclosed |
| US-4565843-A | Lacquer solutions based on hydantoin group-containing polymers | BAYER AKTIENGESELLSCHAFT (DE) | 1986-01-21 | — | — | US | disclosed |
| EP-0150440-A2 | Enamel mixtures based on hydantoin group containing polymers and their application | BAYER AG (DE) | 1985-08-07 | — | — | EP | disclosed |
| US-4517353-A | Process for preparation of hydantoin esters through a masked polyisocyanate-carbodiimide route | BAYER AKTIENGESELLSCHAFT (DE) | 1985-05-14 | — | — | US | disclosed |
| EP-0112528-A2 | Process for the production of hydantoin esters | BAYER AG (DE) | 1984-07-04 | — | — | EP | disclosed |