SCHEMBL8614764

SCHEMBL8614764

CC(C)N(C(=O)O)c1ccccc1CBr

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
LMNA P02545 1/20 0.44
TP53 P04637 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
MLYCD O95822 1/20 0.38
PGR P06401 1/20 0.38
ADRA2A P08913 1/20 0.38
ADRA2B P18089 1/20 0.38
HTR2A P28223 1/20 0.38
HRH1 P35367 1/20 0.38
KCNH2 Q12809 1/20 0.38
HPGD P15428 2/20 0.37
PTPN1 P18031 1/20 0.37
GSK3B P49841 1/20 0.37
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
KDM4E B2RXH2 1/20 0.35
RAB9A P51151 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4510192 0.79 ALDH1A1 (0.38) ALDH1A1TP53SMN1; SMN2MEN1KMT2A
SCHEMBL6700583 0.76 TSHR (0.46) ALDH1A1LMNATP53MEN1KMT2A
SCHEMBL4333889 0.75 ALDH1A1 (0.46) ALDH1A1LMNATP53SMN1; SMN2HPGD
SCHEMBL829847 0.75 ALDH1A1 (0.46) ALDH1A1LMNATP53SMN1; SMN2MEN1
SCHEMBL8885290 0.75 HSD11B1 (0.44) ALDH1A1LMNATP53SMN1; SMN2MEN1
SCHEMBL3567302 0.75 CES2 (0.36) ALDH1A1LMNASMN1; SMN2MEN1KMT2A
SCHEMBL11517103 0.72 SIGMAR1 (0.47) ALDH1A1LMNATP53SMN1; SMN2MEN1
SCHEMBL8779567 0.72 KMT2A (0.49) ALDH1A1SMN1; SMN2MEN1KMT2AHPGD
SCHEMBL2543696 0.71 ALDH1A1 (0.63) ALDH1A1LMNATP53SMN1; SMN2MEN1
Acetic Acid SCHEMBL5351519 0.71 ALDH1A1 (0.46) ALDH1A1LMNASMN1; SMN2PTPN1GSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5824705-A FUNGICIDES BASF AKTIENGESELLSCHAFT (DE) 1998-10-20 US disclosed