Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13499618 | 0.89 | PPARD (0.39) | LMNAALDH1A1KMT2A | |
| SCHEMBL1461137 | 0.87 | ALDH1A1 (0.36) | LMNAALDH1A1MAPTHTTMEN1 | |
| SCHEMBL21734285 | 0.87 | LMNA (0.33) | LMNAALDH1A1MAPTKMT2ATSHR | |
| SCHEMBL2371805 | 0.87 | LMNA (0.34) | LMNAALDH1A1TP53MAPTKMT2A | |
| SCHEMBL14351893 | 0.86 | APP (0.43) | LMNAPOLBALDH1A1MAPTHTT | |
| SCHEMBL21734286 | 0.85 | NISCH (0.42) | ALDH1A1MAPTHTTGAATSHR | |
| SCHEMBL14352104 | 0.85 | TSHR (0.41) | POLBALDH1A1MAPTMEN1GAA | |
| SCHEMBL6130271 | 0.84 | IDO1 (0.46) | ALDH1A1 | |
| SCHEMBL14351850 | 0.79 | MEN1 (0.51) | ALDH1A1HTTMEN1KMT2ATSHR | |
| SCHEMBL8178829 | 0.79 | KMT2A (0.42) | LMNAALDH1A1TP53MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1845086-B1 | N-(2-substituted phenyl)-N-methoxycarbamates and their preparation and use thereof | SHENYANG RES INST CHEMICAL IND (CN) | 2013-04-24 | — | — | EP | disclosed |
| EP-1884511-B1 | AROMATIC ETHER COMPOUNDS,PREPARATION AND USAGE THEREOF | SHENYANG RES INST CHEMICAL IND (CN) | 2012-01-18 | — | — | EP | disclosed |