Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22645131 | 0.83 | ADRB2 (0.39) | SMN1; SMN2GBA1ADRB2ADRB1ADRB3 | |
| SCHEMBL17274170 | 0.74 | GBA1 (0.33) | SMN1; SMN2GBA1ADRB2ADRB1ADRB3 | |
| SCHEMBL11429321 | 0.70 | — | — | |
| SCHEMBL26313837 | 0.69 | — | — | |
| SCHEMBL17931096 | 0.67 | GBA1 (0.33) | GBA1 | |
| SCHEMBL11953312 | 0.67 | EPHX2 (0.33) | SMN1; SMN2 | |
| SCHEMBL16817849 | 0.65 | GBA1 (0.38) | GBA1 | |
| SCHEMBL16769995 | 0.65 | PPP5C (0.37) | SMN1; SMN2GBA1ADRB2ADRB1ADRB3 | |
| SCHEMBL16711496 | 0.65 | GBA1 (0.38) | SMN1; SMN2GBA1ADRB2ADRB1ADRB3 | |
| SCHEMBL19599988 | 0.64 | ADRB2 (0.33) | GBA1ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3647304-B1 | METHOD FOR PREPARING 2-FLUOROACRYLATE | LINHAI TIANYU PHARMACEUTICAL CO LTD (CN) | 2021-11-03 | — | — | EP | disclosed |
| US-10844000-B2 | Method for preparing 2-fluoroacrylates | LINHAI TIANYU PHARMACEUTICAL CO., LTD. (CN) | 2020-11-24 | — | — | US | disclosed |
| EP-3647304-A1 | METHOD FOR PREPARING 2-FLUOROACRYLATE | Linhai Tianyu Pharmaceutical Co., Ltd. (CN) | 2020-05-06 | — | — | EP | disclosed |
| US-20200123095-A1 | METHOD FOR PREPARING 2-FLUOROACRYLATES | LINHAI TIANYU PHARMACEUTICAL CO., LTD. (CN) | 2020-04-23 | — | — | US | disclosed |
| EP-0127920-B1 | A PROCESS FOR PREPARING AN ALKYLENE COMPOUND STARTING FROM A FLUOROCYCLOPROPANE COMPOUND | SHIONOGI & CO., LTD. (JP) | 1988-01-27 | — | — | EP | disclosed |
| US-4570018-A | INTERMEDIATES FOR CEPHALOSPORINS | SHIONOGI & CO., LTD. (JP) | 1986-02-11 | — | — | US | disclosed |
| EP-0127920-A2 | A process for preparing an alkylene compound starting from a fluorocyclopropane compound | SHIONOGI & CO., LTD. (JP) | 1984-12-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200123095-A1 | METHOD FOR PREPARING 2-FLUOROACRYLATES | FGB, CYP2F1, ESD | SMN1; SMN2 4430/4885GBA1 2844/4885ADRB2 1613/4885 |
| US-10844000-B2 | Method for preparing 2-fluoroacrylates | FGB, CYP2F1, ESD | SMN1; SMN2 4430/4885GBA1 2844/4885ADRB2 1613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.