Methacrylic Acid

Methacrylic Acid

SCHEMBL10705654

C=C(C)C(=O)O.C=C(C)C(=O)O.CCCCC(CC)CC(O)CO

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.47
CA2 P00918 3/20 0.40
TSHR P16473 3/20 0.39
CYP3A4 P08684 3/20 0.37
TDP1 Q9NUW8 2/20 0.37
ATM Q13315 1/20 0.37
MAPK1 P28482 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
LMNA P02545 1/20 0.35
GPR84 Q9NQS5 4/20 0.34
HDAC3 O15379 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC7 Q8WUI4 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC10 Q969S8 1/20 0.33
HDAC11 Q96DB2 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
HDAC9 Q9UKV0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL28221265 1.00 ALDH1A1 (0.47) ALDH1A1CA2TSHRCYP3A4TDP1
Methacrylic Acid SCHEMBL14718311 0.85 ALDH1A1 (0.67) ALDH1A1CA2TSHRCYP3A4TDP1
SCHEMBL2388866 0.85 ALDH1A1 (0.64) ALDH1A1CA2TSHRCYP3A4TDP1
SCHEMBL27678371 0.85 ALDH1A1 (0.64) ALDH1A1CA2TSHRCYP3A4TDP1
Acrylic Acid SCHEMBL28145070 0.84 TSHR (0.49) ALDH1A1CA2TSHRCYP3A4TDP1
Methacrylic Acid SCHEMBL18526885 0.83 GPR84 (0.44) ALDH1A1CA2MAPK1LMNAGPR84
Methacrylic Acid SCHEMBL9779338 0.83 GPR84 (0.44) ALDH1A1CA2MAPK1LMNAGPR84
Methacrylic Acid SCHEMBL730446 0.83 GPR84 (0.44) ALDH1A1CA2MAPK1LMNAGPR84
Methacrylic Acid SCHEMBL27858349 0.82 MMP9 (0.39) ALDH1A1CA2TSHRCYP3A4TDP1
Methacrylic Acid SCHEMBL28233783 0.82 CA2 (0.50) ALDH1A1CA2TSHRCYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0105639-B1 PRODUCTION OF RESISTOR FROM INSULATING MATERIAL BY LOCAL HEATING KABUSHIKI KAISHA TOSHIBA (JP) 1988-01-07 EP disclosed
US-4584456-A Production of resistor from insulating material by local heating TOKYO SHIBAURA DENKI KABUSHIKI KAISHA (JP) 1986-04-22 US disclosed
EP-0105639-A2 Production of resistor from insulating material by local heating KABUSHIKI KAISHA TOSHIBA (JP) 1984-04-18 EP disclosed