Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 3/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.36 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3668334 | 0.82 | CYP1A2 (0.52) | ELANECYP1A2CYP2D6HPGDCYP2C19 | |
| SCHEMBL6524959 | 0.81 | MEN1 (0.43) | KMT2AMEN1ELANETDP1 | |
| SCHEMBL12677608 | 0.79 | TUBB4A (0.59) | DRD2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5052728 | 0.79 | ELANE (0.38) | KMT2AMEN1DRD2ELANEHPGD | |
| SCHEMBL8940576 | 0.78 | CA12 (0.51) | DRD2HPGD | |
| SCHEMBL9170217 | 0.78 | PDE4A (0.53) | KMT2AMEN1PDE4APDE4BPDE4C | |
| SCHEMBL12574107 | 0.76 | PDE4A (0.48) | DRD2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2281109 | 0.74 | MEN1 (0.39) | KMT2AMEN1 | |
| SCHEMBL25189253 | 0.74 | PREP (0.43) | KMT2AMEN1DRD2PDE4APDE4B | |
| SCHEMBL9688347 | 0.74 | DRD2 (0.40) | DRD2PDE4DCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448980-B1 | POLYMERS FUNCTIONALIZED WITH HYDROXYL GROUP-CONTAINING DIPHENYLETHYLENE | BRIDGESTONE CORP (JP) | 2015-02-11 | — | — | EP | disclosed |
| US-8765888-B2 | Polymers functionalized with hydroxyl group-containing diphenylethylene | BRIDGESTONE CORPORATION (JP) | 2014-07-01 | — | — | US | disclosed |
| US-20120130009-A1 | POLYMERS FUNCTIONALIZED WITH HYDROXYL GROUP-CONTAINING DIPHENLYETHYLENE | BRIDGESTONE CORPORATION (JP) | 2012-05-24 | — | — | US | disclosed |
| EP-2448980-A2 | POLYMERS FUNCTIONALIZED WITH HYDROXYL GROUP-CONTAINING DIPHENYLETHYLENE | Bridgestone Corporation (JP) | 2012-05-09 | — | — | EP | disclosed |
| WO-2011002830-A2 | POLYMERS FUNCTIONALIZED WITH HYDROXYL GROUP-CONTAINING DIPHENYLETHYLENE | BRIDGESTONE CORPORATION (JP) | 2011-01-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120130009-A1 | POLYMERS FUNCTIONALIZED WITH HYDROXYL GROUP-CONTAINING DIPHENLYETHYLENE | VCL, PGR, CD44 | KMT2A 2411/4885MEN1 4176/4885DRD2 844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.