Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 6/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10706345 | 1.00 | TDP1 (0.45) | TDP1TAS1R3TAS1R1APPHRH3 | |
| SCHEMBL17138167 | 0.73 | GAA (0.56) | TDP1TAS1R3TAS1R1NPSR1GAA | |
| SCHEMBL10705151 | 0.72 | APP (0.57) | APPHRH3 | |
| SCHEMBL9637404 | 0.71 | APP (0.70) | APPHRH3MAPTHPGDKDM4E | |
| SCHEMBL9637407 | 0.71 | APP (0.70) | APPHRH3MAPTHPGDKDM4E | |
| SCHEMBL17138171 | 0.70 | GAA (0.49) | TDP1NPSR1GAAXBP1ATM | |
| SCHEMBL6990016 | 0.69 | TOP2A (0.47) | APPNPSR1GAAXBP1ATM | |
| 4-Methoxycinnamic Acid SCHEMBL11270862 | 0.68 | TDP1 (0.62) | TDP1TAS1R3TAS1R1GAAATM | |
| 4-Methoxycinnamic Acid SCHEMBL28527848 | 0.68 | THRB (0.62) | TDP1TAS1R3TAS1R1ATMSMN1; SMN2 | |
| 4-Methoxycinnamic Acid SCHEMBL1463076 | 0.68 | THRB (0.62) | TDP1TAS1R3TAS1R1ATMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63277670-A | — | — | None | — | — | JP | disclosed |
| JP-S63277670-A | ESTERIFIED PRODUCTION OF 5-HYDROXY-2-STYRYL-4-PYRONE DERIVATIVE | PIASUARAIZU KK | 1988-11-15 | — | — | JP | disclosed |