SCHEMBL1070656

SCHEMBL1070656

Oc1n[c]c2ccccc2c1O

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.33
PTPN22 Q9Y2R2 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
CACNA1B Q00975 1/20 0.31
APBA1 Q02410 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1065946 0.70 CYP1A2 (0.33) IDO1PTPN22KDM4E
SCHEMBL4574784 0.69 IDO1 (0.41) IDO1PTPN22KDM4EMEN1ALDH1A1
SCHEMBL24030 0.68 GPR3 (0.46) KDM4EALDH1A1GAAMAPTKMT2A
SCHEMBL559155 0.67 GPR3 (0.35) ALDH1A1
SCHEMBL1396389 0.65 IDO1 (0.38) IDO1PTPN22KDM4EMEN1ALDH1A1
SCHEMBL558999 0.65 MAOA (0.37)
SCHEMBL17908518 0.64 TYMS (0.37) ALDH1A1MAPT
SCHEMBL6359371 0.64
SCHEMBL2514493 0.63 GPR3 (0.34) KDM4EALDH1A1GAAMAPTKMT2A
SCHEMBL2514483 0.63 LMNA (0.37) IDO1KDM4EALDH1A1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150159009-A1 GRAFT COPOLYMERS, THEIR PREPARATION AND USE IN CAPILLARY ELECTROPHORESIS APPLIED BIOSYSTEMS LLC (US) 2015-06-11 US disclosed
US-8784627-B2 Graft copolymers, their preparation and use in capillary electrophoresis APPLIED BIOSYSTEMS, LLC (US) 2014-07-22 US disclosed
US-20130153421-A1 GRAFT COPOLYMERS, THEIR PREPARATION AND USE IN CAPILLARY ELECTROPHORESIS APPLIED BIOSYSTEMS, LLC (US) 2013-06-20 US disclosed
EP-2275463-A1 Support for electrophoresis containing a composition and method Life Technologies Corporation (US) 2011-01-19 EP disclosed
EP-1539846-B1 GRAFT COPOLYMERS, THEIR PREPARATION AND USE IN CAPILLARY ELECTROPHORESIS LIFE TECHNOLOGIES CORP (US) 2010-09-08 EP disclosed
US-20100187111-A1 Graft Copolymers, Their Preparation And Use in Capillary Electrophoresis Life Technologies Corporation (US) 2010-07-29 US disclosed
EP-2182014-A1 Method for making poly(N,N-dimethylacrylamide) and poly(N,N-dimethylacrylamide) Applera Corporation (US) 2010-05-05 EP disclosed
US-20050234166-A1 Graft copolymers, their preparation and use in capillary electrophoresis APPLIED BIOSYSTEMS, INC. 2005-10-20 US disclosed
EP-1539846-A1 GRAFT COPOLYMERS, THEIR PREPARATION AND USE IN CAPILLARY ELECTROPHORESIS Applera Corporation (US) 2005-06-15 EP disclosed
WO-2004011513-A1 GRAFT COPOLYMERS, THEIR PREPARATION AND USE IN CAPILLARY ELECTROPHORESIS APPLERA CORPORATION (US) 2004-02-05 WO disclosed