SCHEMBL24030

SCHEMBL24030

[c]1nc2ccccc2c2ccccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 3/20 0.46
KDM4E B2RXH2 5/20 0.37
ALDH1A1 P00352 3/20 0.34
MAOA P21397 2/20 0.34
GLA P06280 2/20 0.34
HPGD P15428 2/20 0.34
CASP1 P29466 2/20 0.34
CASP7 P55210 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
HSD17B10 Q99714 2/20 0.34
ACHE P22303 2/20 0.34
CHRM2 P08172 1/20 0.34
ADRA2A P08913 1/20 0.34
ADORA3 P0DMS8 1/20 0.34
CHRM1 P11229 1/20 0.34
NQO2 P16083 1/20 0.34
DRD1 P21728 1/20 0.34
SLC6A2 P23975 1/20 0.34
ADRA1A P35348 1/20 0.34
OPRM1 P35372 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2514493 0.83 GPR3 (0.34) GPR3KDM4EALDH1A1MAOAGLA
SCHEMBL15578037 0.80 ACHE (0.39) GPR3KDM4EALDH1A1MAOAHPGD
SCHEMBL15578212 0.80 KDM4E (0.39) GPR3KDM4EALDH1A1MAOAHPGD
SCHEMBL15578381 0.80 KDM4E (0.39) GPR3KDM4EALDH1A1MAOAHPGD
SCHEMBL15578202 0.80 ACHE (0.39) KDM4EALDH1A1MAOAHPGDCASP1
SCHEMBL7790782 0.79 ESR1 (0.42) GPR3KDM4EALDH1A1MAOAGLA
SCHEMBL2520862 0.76 LMNA (0.43) KDM4EALDH1A1SMN1; SMN2TDP1MAPT
SCHEMBL1387044 0.76 HSP90AA1 (0.39) KDM4EALDH1A1SMN1; SMN2TDP1MAPT
SCHEMBL1384101 0.76 PARP1 (0.33) GPR3KDM4ESMN1; SMN2MAPTKMT2A
SCHEMBL2515544 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4329 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118324771-A Organic light-emitting device, electronic device, and heterocyclic compound 三星显示有限公司 2024-07-12 CN claimed
CN-118284082-A Light emitting device, electronic device including the same, and electronic apparatus including the same 三星显示有限公司 2024-07-02 CN claimed
US-20240188432-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2024-06-06 US claimed
CN-118139509-A Organic electroluminescent device 长春海谱润斯科技股份有限公司 2024-06-04 CN claimed
US-20240174694-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2024-05-30 US claimed
US-11976086-B2 Organometallic compound, organic light-emitting device including the organometallic compound, and apparatus including the organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2024-05-07 US claimed
US-20240138260-A1 PLURALITY OF HOST MATERIALS, ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2024-04-25 US claimed
CN-117903189-A Carbazole compound and organic electroluminescent device thereof 长春海谱润斯科技股份有限公司 2024-04-19 CN claimed
US-11950506-B2 Plurality of host materials and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2024-04-02 US claimed
US-11944006-B2 Diamine compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2024-03-26 US claimed
US-5622961-A PROSTATE CANCER, SKIN DISORDERS, BALDNESS ELI LILLY AND COMPANY (US) 1997-04-22 US claimed
US-5578724-A INHIBITORS OF 5-ALPHA-REDUCTASE ELI LILLY AND COMPANY (US) 1996-11-26 US claimed
WO-1996035422-A1 METHODS FOR INHIBITING BONE LOSS ELI LILLY AND COMPANY (US) 1996-11-14 WO claimed
EP-0742010-A2 Benzoquinolin-3-ones to inhibit bone loss ELI LILLY AND COMPANY (US) 1996-11-13 EP claimed
US-5569763-A USEFUL AS ORGANIC NONLINEAR OPTICAL MATERIAL AND A HIGHLY SENSITIVE COLORING CHELATION AGENT KABUSHIKI KAISHA TOSHIBA (JP) 1996-10-29 US claimed
EP-0733365-A2 Use of benzoquinolin-3-ones for the treatment and prevention of prostatic cancer ELI LILLY AND COMPANY (US) 1996-09-25 EP claimed
US-5550134-A ADMINISTERING TO A MAMMAL FROM A SERIES OF BENZOQUINOLIN-3-ONE COMPOUNDS ELI LILLY AND COMPANY (US) 1996-08-27 US claimed
WO-1996009046-A1 5α-REDUCTASE INHIBITORS ELI LILLY AND COMPANY (US) 1996-03-28 WO claimed
EP-0703221-A1 5 alpha-reductase Inhibitors ELI LILLY AND COMPANY (US) 1996-03-27 EP claimed
US-5204470-A AZABICYCLIC DERIVATIVES JOHN WYETH & BROTHER, LIMITED (GB) 1993-04-20 US claimed