Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25317526 | 0.83 | ALDH1A1 (0.47) | ALDH1A1CYP1A2LMNANPSR1CYP2C9 | |
| SCHEMBL9211 | 0.83 | ALDH1A1 (0.49) | ALDH1A1CYP1A2LMNANPSR1CYP2C9 | |
| SCHEMBL1684350 | 0.83 | ALDH1A1 (0.49) | ALDH1A1CYP1A2LMNANPSR1CYP2C9 | |
| SCHEMBL18982867 | 0.83 | ALDH1A1 (0.49) | ALDH1A1CYP1A2LMNANPSR1CYP2C9 | |
| SCHEMBL23291809 | 0.81 | ALDH1A1 (0.48) | ALDH1A1CYP1A2LMNANPSR1CYP2C9 | |
| SCHEMBL11384534 | 0.81 | ALDH1A1 (0.50) | ALDH1A1CYP1A2LMNANPSR1CYP2C9 | |
| SCHEMBL31619451 | 0.80 | CES2 (0.47) | ALDH1A1CYP1A2LMNANPSR1CYP2C9 | |
| SCHEMBL6135476 | 0.80 | NPSR1 (0.50) | ALDH1A1CYP1A2LMNANPSR1CYP2C9 | |
| SCHEMBL204187 | 0.80 | NPSR1 (0.50) | ALDH1A1CYP1A2LMNANPSR1CYP2C9 | |
| SCHEMBL6135621 | 0.80 | NPSR1 (0.50) | ALDH1A1CYP1A2LMNANPSR1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0168619-B1 | N-ACYLATED DI- OR TETRAHYDRONAPHTHALENAMINES, AND ANTIHYPERTENSIVE COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1988-08-24 | — | — | EP | disclosed |