Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11210582 | 0.88 | MC4R (0.51) | MC4RITGA4ITGB7CTSLALDH1A1 | |
| SCHEMBL13150768 | 0.78 | L3MBTL1 (0.43) | ITGA4ITGB7ALDH1A1SLC15A1 | |
| SCHEMBL29077734 | 0.77 | L3MBTL1 (0.50) | ALDH1A1MAPTKMT2ATDP1 | |
| SCHEMBL5724173 | 0.77 | ALDH1A1 (0.54) | ALDH1A1MAPTRAB9ANR1D1 | |
| SCHEMBL7737719 | 0.76 | RAB9A (0.55) | MC4RITGA4ITGB7CTSLRAB9A | |
| SCHEMBL5724430 | 0.76 | ALDH1A1 (0.48) | ALDH1A1MAPTRAB9ANR1D1MMP2 | |
| SCHEMBL9706834 | 0.75 | MC4R (0.51) | MC4RITGA4ITGB7CTSLRAB9A | |
| SCHEMBL8251477 | 0.75 | ITGA4 (0.49) | MC4RITGA4ITGB7ALDH1A1MAPT | |
| SCHEMBL2502338 | 0.75 | ITGA4 (0.49) | MC4RITGA4ITGB7ALDH1A1MAPT | |
| SCHEMBL10598042 | 0.73 | HTR2A (0.41) | MC4RITGA4ITGB7CTSLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117089-B1 | BETA-ADRENERGIC ANTAGONIST COMPOUNDS AND DERIVATIVES OF BETA-ADRENERGIC ANTAGONISTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1988-12-14 | — | — | EP | disclosed |