Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10708312 | 1.00 | TRPM8 (0.38) | TRPM8L3MBTL1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL9219750 | 0.94 | L3MBTL1 (0.41) | L3MBTL1ALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL25381770 | 0.86 | L3MBTL1 (0.39) | L3MBTL1ALDH1A1LMNAHSD17B10TDP1 | |
| SCHEMBL16732371 | 0.86 | METAP2 (0.40) | L3MBTL1ALDH1A1CYP2D6NPSR1 | |
| SCHEMBL1009487 | 0.86 | L3MBTL1 (0.39) | L3MBTL1ALDH1A1LMNAHSD17B10CYP2D6 | |
| SCHEMBL11021965 | 0.85 | METAP2 (0.43) | L3MBTL1ALDH1A1NPSR1 | |
| SCHEMBL4138474 | 0.85 | ALDH1A1 (0.38) | TRPM8L3MBTL1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL4425794 | 0.85 | METAP2 (0.43) | L3MBTL1ALDH1A1NPSR1 | |
| SCHEMBL11320136 | 0.81 | CPN1 (0.45) | L3MBTL1ALOX15 | |
| SCHEMBL10707623 | 0.81 | TP53 (0.42) | L3MBTL1ALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0152697-B1 | HETEROCYCLICALLY SUBSTITUTED ETHANES AND THEIR USE IN LIQUID CRYSTAL MATERIALS AND DEVICES | The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) | 1988-12-07 | — | — | EP | disclosed |
| US-4698176-A | Heterocyclically substituted ethanes and their use in liquid crystal materials and devices | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1987-10-06 | — | — | US | disclosed |
| US-4632515-A | Heterocyclically substituted ethanes and their use in liquid crystal materials and devices | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1986-12-30 | — | — | US | disclosed |
| EP-0152697-A1 | Heterocyclically substituted ethanes and their use in liquid crystal materials and devices | The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) | 1985-08-28 | — | — | EP | disclosed |