Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | PTGES2 | Q9H7Z7 | 6/20 | 0.45 |
| ▸ | UQCRB | P14927 | 1/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.45 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.42 |
| ▸ | DDX3X | O00571 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28215783 | 0.83 | PARP14 (0.52) | GAAMEN1KMT2AHTTMAPT | |
| SCHEMBL9488680 | 0.81 | EP300 (0.61) | GAAMEN1KMT2AHTTMAPT | |
| SCHEMBL4965384 | 0.81 | GAA (0.49) | GAAMEN1KMT2AHTTMAPT | |
| SCHEMBL11871635 | 0.80 | PGAM1 (0.57) | GAAMEN1KMT2AHTTMAPT | |
| SCHEMBL11442426 | 0.79 | PGAM1 (0.52) | — | |
| SCHEMBL10808948 | 0.79 | KEAP1 (0.57) | GAAMEN1KMT2AHTTMAPT | |
| SCHEMBL9502605 | 0.79 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1POLB | |
| SCHEMBL6566936 | 0.78 | CA1 (0.56) | GAAMEN1KMT2AHTTMAPT | |
| SCHEMBL10886862 | 0.78 | PGAM1 (0.51) | — | |
| SCHEMBL9821282 | 0.78 | PTGES2 (0.52) | MEN1KMT2AHTTPTGES2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0144701-B1 | PROCESS FOR THE PREPARATION OF 2-AMINO-1-HYDROXY-4-OR-5-(BETA-SULFATOETHYLSULFONYL)-BENZENE COMPOUNDS AND THEIR USE FOR THE SYNTHESIS OF FIBER-REACTIVE COMPOUNDS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-03-16 | — | — | EP | disclosed |
| EP-0144701-A2 | Process for the preparation of 2-amino-1-hydroxy-4-or-5-(beta-sulfatoethylsulfonyl)-benzene compounds and their use for the synthesis of fiber-reactive compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-06-19 | — | — | EP | disclosed |
| EP-0035956-B1 | PROCESS FOR THE PREPARATION OF SULFATOETHYLSULFONYL COMPOUNDS | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-02-16 | — | — | EP | disclosed |
| EP-0035956-A1 | Process for the preparation of sulfatoethylsulfonyl compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-09-16 | — | — | EP | disclosed |