Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 2/20 | 0.61 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.61 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.61 |
| ▸ | HKDC1 | Q2TB90 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | IDO1 | P14902 | 6/20 | 0.51 |
| ▸ | BRAF | P15056 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | CASP1 | P29466 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10408858 | 0.83 | EP300 (0.70) | EP300KAT2BKAT8HKDC1MEN1 | |
| SCHEMBL10708486 | 0.81 | GAA (0.49) | MEN1KMT2AGAAALDH1A1TP53 | |
| SCHEMBL25989098 | 0.81 | EP300 (0.58) | EP300KAT2BKAT8MEN1KMT2A | |
| SCHEMBL11640095 | 0.79 | EP300 (0.59) | EP300KAT2BKAT8HKDC1MEN1 | |
| SCHEMBL10808948 | 0.79 | KEAP1 (0.57) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL9769697 | 0.78 | EP300 (0.71) | EP300KAT2BKAT8HKDC1MEN1 | |
| SCHEMBL15894583 | 0.76 | EP300 (1.00) | EP300KAT2BKAT8HKDC1MEN1 | |
| SCHEMBL30669737 | 0.76 | EP300 (1.00) | EP300KAT2BKAT8HKDC1MEN1 | |
| SCHEMBL589708 | 0.73 | HKDC1 (0.77) | EP300KAT2BKAT8HKDC1MEN1 | |
| SCHEMBL9807346 | 0.70 | CA1 (0.50) | MEN1KMT2AIDO1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5229502-A | PREPARATION OF 1:2 CHROMIUM COMPLEXES ONE SULFO SUBSTITUTED AND ONE SULFONAMIDO OR THE LIKE SUBSTITUTED AZO DYES | CIBA-GEIGY CORPORATION (US) | 1993-07-20 | — | — | US | disclosed |