Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9807354 | 0.81 | ALDH1A1 (0.36) | TGFBR1CYP1A2TSHRALDH1A1CYP2C19 | |
| SCHEMBL6259132 | 0.81 | CYP1A2 (0.41) | CYP1A2TDP1KDM4ETSHRALDH1A1 | |
| SCHEMBL1070950 | 0.81 | SMN1; SMN2 (0.42) | TGFBR1KDM4ETSHRALDH1A1KMT2A | |
| SCHEMBL733022 | 0.81 | CHRM5 (0.40) | TGFBR1CYP1A2RXFP1SIGMAR1 | |
| SCHEMBL20081800 | 0.75 | TSHR (0.48) | CYP1A2TDP1KDM4ETSHRALDH1A1 | |
| SCHEMBL27897257 | 0.69 | CA12 (0.53) | CYP1A2TDP1CA12CA2CA9 | |
| SCHEMBL5529837 | 0.68 | CYP1A2 (0.36) | CYP1A2TDP1KDM4ETSHRALDH1A1 | |
| SCHEMBL24333197 | 0.67 | TGFBR1 (0.50) | TGFBR1TDP1KDM4ETSHRALDH1A1 | |
| SCHEMBL14951 | 0.67 | — | — | |
| SCHEMBL8771130 | 0.67 | LMNA (0.43) | TGFBR1CYP1A2TSHRCA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423487-B2 | ACYCLIC OR HETEROCYCLIC AMINOALKYL (METH)ACRYLAMIDE POLYMERS OR POLYMERS OF (METH)ACRYLATED ALKYLENE OXIDE ADDUCTS OF PIPERAZINES OR MORPHOLINE AS VISCOSITY ENHANCERS | FUJI PHOTO FILM CO., LTD. (JP) | 2002-07-23 | — | — | US | disclosed |
| US-20020015927-A1 | Thermally processed image recording material | FUJIFILM CORPORATION (JP) | 2002-02-07 | — | — | US | disclosed |