Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 12/20 | 0.51 |
| ▸ | DRD2 | P14416 | 10/20 | 0.51 |
| ▸ | DRD5 | P21918 | 9/20 | 0.51 |
| ▸ | DRD4 | P21917 | 4/20 | 0.51 |
| ▸ | DRD3 | P35462 | 7/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10709628 | 0.81 | DRD1 (0.54) | DRD1DRD2DRD5DRD4DRD3 | |
| SCHEMBL10701215 | 0.68 | DRD1 (0.53) | DRD1DRD2DRD5DRD4DRD3 | |
| SCHEMBL9563677 | 0.67 | ALDH1A1 (0.39) | THPOHIF1AHSD17B10MTORKDM4E | |
| SCHEMBL11765918 | 0.66 | ALOX5 (0.45) | MAPK1HSD17B10KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL5944480 | 0.66 | DRD1 (0.50) | DRD1DRD2DRD5DRD4DRD3 | |
| SCHEMBL5988956 | 0.66 | TRPA1 (0.47) | MAPK1HSD17B10KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL5988961 | 0.66 | TRPA1 (0.47) | MAPK1HSD17B10KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL5988966 | 0.66 | TRPA1 (0.47) | MAPK1HSD17B10KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL19236385 | 0.65 | DRD1 (0.53) | DRD1DRD2DRD5DRD4DRD3 | |
| SCHEMBL6247473 | 0.65 | DRD2 (0.62) | DRD1DRD2DRD5DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0285287-A2 | 3-Benzazepine compounds for use in treating gastrointestinal motility disorders | SMITHKLINE BEECHAM CORPORATION (US) | 1988-10-05 | — | — | EP | disclosed |