SCHEMBL29424499

SCHEMBL29424499

CCOP(=S)(OCC)SC(CCl)N1C(=O)c2ccccc2C1=O

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PLIN1 O60240 1/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPT P10636 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
PLIN5 Q00G26 1/20 0.41
ABHD5 Q8WTS1 1/20 0.41
TDP1 Q9NUW8 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3728876 1.00 PLIN1 (0.41) PLIN1ALDH1A1MAPTHPGDALOX15
SCHEMBL122099 1.00 PLIN1 (0.41) PLIN1ALDH1A1MAPTHPGDALOX15
Dimethyl Sulfone SCHEMBL19032723 0.95 ALDH1A1 (0.38) PLIN1ALDH1A1MAPTHPGDALOX15
Phosmet SCHEMBL1070968 0.88 ALDH1A1 (0.63) PLIN1ALDH1A1MAPTHPGDALOX15
SCHEMBL9745780 0.85 ELANE (0.37) TDP1
SCHEMBL11688456 0.82 ALDH1A1 (0.43) PLIN1ALDH1A1MAPTHPGDALOX15
Phosmet SCHEMBL1070798 0.80 ALDH1A1 (0.53) PLIN1ALDH1A1MAPTHPGDALOX15
SCHEMBL8806099 0.79 ALDH1A1 (0.39) PLIN1ALDH1A1MAPTHPGDALOX15
SCHEMBL8806093 0.75 ALDH1A1 (0.37) PLIN1ALDH1A1MAPTHPGDALOX15
SCHEMBL13596981 0.68 ALDH1A1 (0.81) PLIN1ALDH1A1MAPTHPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022230804-A1 AGRICULTURAL AND HORTICULTURAL FUNGICIDAL COMPOSITION 日本曹達株式会社 2022-11-03 WO claimed
EP-4658079-A2 PESTICIDAL COMPOUNDS AND THEIR USE Greenlight Biosciences, Inc. (US) 2025-12-10 EP disclosed
WO-2025103215-A1 FOUR-MEMBERED-RING AMIDE COMPOUNDS AND USE THEREOF 青岛清原化合物有限公司 2025-05-22 WO disclosed
WO-2025067191-A1 FOUR-MEMBERED RING AMIDE COMPOUND AND USE THEREOF 青岛清原化合物有限公司 2025-04-03 WO disclosed
WO-2025056007-A1 FOUR-MEMBERED RING AMIDE COMPOUNDS AND USE THEREOF 青岛清原化合物有限公司 2025-03-20 WO disclosed
WO-2025051203-A1 FOUR-MEMBERED CYCLIC AMIDE COMPOUND AND USE THEREOF 青岛清原化合物有限公司 2025-03-13 WO disclosed
WO-2025026292-A1 4-MEMBERED CYCLIC AMIDE COMPOUND AND USE THEREOF 青岛清原化合物有限公司 2025-02-06 WO disclosed
US-12172999-B2 Polymorphs SYNGENTA CROP PROTECTION AG (CH) 2024-12-24 US disclosed
US-12134614-B2 Polymorphs SYNGENTA CROP PROTECTION AG (CH) 2024-11-05 US disclosed
WO-2024163899-A2 PESTICIDAL COMPOUNDS AND THEIR USE GREENLIGHT BIOSCIENCES, INC. (US) 2024-08-08 WO disclosed
US-20230151009-A1 POLYMORPHS SYNGENTA PARTICIPATIONS AG (CH) 2023-05-18 US disclosed
US-11572361-B2 Polymorphs SYNGENTA PARTICIPATIONS AG (CH) 2023-02-07 US disclosed
WO-2022254622-A1 AGRICULTURAL/HORTICULTURAL INSECTICIDE COMPOSITION AND AGRICULTURAL/HORTICULTURAL INSECT PEST CONTROL METHOD 株式会社エス・ディー・エス バイオテック 2022-12-08 WO disclosed
WO-2022230804-A1 AGRICULTURAL AND HORTICULTURAL FUNGICIDAL COMPOSITION 日本曹達株式会社 2022-11-03 WO disclosed
US-20220048873-A1 PESTICIDALLY ACTIVE CYCLOPROPYL METHYL AMIDE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2022-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11572361-B2 Polymorphs CYP4F2, CYP1B1, CYP3A43 PLIN1 1635/4885ALDH1A1 216/4885MAPT 1068/4885
US-12134614-B2 Polymorphs CYP3A43, CYP4F2, CYP1B1 PLIN1 1744/4885ALDH1A1 209/4885MAPT 1118/4885
US-12172999-B2 Polymorphs CYP3A43, CYP4F2, CYP1A2 PLIN1 1729/4885ALDH1A1 216/4885MAPT 1083/4885
US-20220048873-A1 PESTICIDALLY ACTIVE CYCLOPROPYL METHYL AMIDE DERIVATIVES ACHE, PNMT, DDT PLIN1 4188/4885ALDH1A1 664/4885MAPT 260/4885
US-20230151009-A1 POLYMORPHS CYP3A43, CYP4F2, CYP1A2 PLIN1 1729/4885ALDH1A1 216/4885MAPT 1083/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.