Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLIN1 | O60240 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.41 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL122099 | 1.00 | PLIN1 (0.41) | PLIN1ALDH1A1MAPTHPGDALOX15 | |
| SCHEMBL29424499 | 1.00 | PLIN1 (0.41) | PLIN1ALDH1A1MAPTHPGDALOX15 | |
| Dimethyl Sulfone SCHEMBL19032723 | 0.95 | ALDH1A1 (0.38) | PLIN1ALDH1A1MAPTHPGDALOX15 | |
| Phosmet SCHEMBL1070968 | 0.88 | ALDH1A1 (0.63) | PLIN1ALDH1A1MAPTHPGDALOX15 | |
| SCHEMBL9745780 | 0.85 | ELANE (0.37) | TDP1 | |
| SCHEMBL11688456 | 0.82 | ALDH1A1 (0.43) | PLIN1ALDH1A1MAPTHPGDALOX15 | |
| Phosmet SCHEMBL1070798 | 0.80 | ALDH1A1 (0.53) | PLIN1ALDH1A1MAPTHPGDALOX15 | |
| SCHEMBL8806099 | 0.79 | ALDH1A1 (0.39) | PLIN1ALDH1A1MAPTHPGDALOX15 | |
| SCHEMBL8806093 | 0.75 | ALDH1A1 (0.37) | PLIN1ALDH1A1MAPTHPGDALOX15 | |
| SCHEMBL13596981 | 0.68 | ALDH1A1 (0.81) | PLIN1ALDH1A1MAPTHPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100168030-A1 | Methods and compositions for treatment of organophosphate-caused pathology | ARMY, UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE | 2010-07-01 | — | — | US | disclosed |
| US-4780457-A | SYNERGISTIC NITROMETHYLENE DERIVATIVE AND CHLORPYRIFOS DERIVATIVE | NIHON TOKUSHI NOYAKU SEIZO K.K. (JP) | 1988-10-25 | — | — | US | disclosed |
| US-4725589-A | SYNERGISTIC BLEND OF NITROMETHYLENE AND ORGANOPHOSPHATE ESTER | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1988-02-16 | — | — | US | disclosed |