SCHEMBL1070992

SCHEMBL1070992

CC(=O)OCC=C(C)CCC=C(C)C=O

nearest known ligand 0.71

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.71
ALOX15 P16050 1/20 0.71
PTPN1 P18031 1/20 0.46
TRPV1 Q8NER1 3/20 0.43
FNTA P49354 2/20 0.43
FNTB P49356 2/20 0.43
PGGT1B P53609 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11785322 1.00 ALDH1A1 (0.71) ALDH1A1ALOX15PTPN1TRPV1FNTA
SCHEMBL1070989 1.00 ALDH1A1 (0.71) ALDH1A1ALOX15PTPN1TRPV1FNTA
SCHEMBL13288245 0.98 ALDH1A1 (0.69) ALDH1A1ALOX15PTPN1TRPV1FNTA
SCHEMBL29586651 0.88 ALDH1A1 (0.54) ALDH1A1ALOX15TRPV1FNTAFNTB
SCHEMBL28410357 0.86 ALDH1A1 (0.71) ALDH1A1ALOX15PTPN1TRPV1FNTA
SCHEMBL30342059 0.85 ALDH1A1 (0.51) ALDH1A1ALOX15TRPV1FNTAFNTB
SCHEMBL10613495 0.84 ALDH1A1 (0.73) ALDH1A1ALOX15PTPN1TRPV1FNTA
SCHEMBL10613500 0.84 ALDH1A1 (0.73) ALDH1A1ALOX15PTPN1TRPV1FNTA
SCHEMBL2560936 0.83 ALDH1A1 (0.72) ALDH1A1ALOX15PTPN1TRPV1FNTA
SCHEMBL2560933 0.83 ALDH1A1 (0.72) ALDH1A1ALOX15PTPN1TRPV1FNTA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6284910-B1 FARNESYL TRANSFERASE INHIBITORS UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION 2001-09-04 US claimed
CN-111269121-B Purification method of 8-oxo-3, 7-dimethyl-2, 6-octadienyl carboxylate compound 广州巨元生化有限公司 2023-04-07 CN disclosed
EP-1879902-B1 COMPOSITION COMPRISING ONE OR MORE LYCOPHYLL DERIVATIVES CARDAX PHARMA INC (US) 2020-01-08 EP disclosed
EP-1797953-B1 PROCESS FOR PRODUCING OXYGENIC COMPOUND SUMITOMO CHEMICAL CO (JP) 2011-01-05 EP disclosed
WO-2009104605-A1 NOVEL INTERMEDIATE FOR SYNTHESIS OF ASCOFRANONE HAVING VARIOUS PHYSIOLOGICAL ACTIVITIES, AND NOVEL SHORTENED TOTAL SYNTHESIS METHOD FOR ASCOFRANONE USING THE SAME アリジェン製薬株式会社 (JP) 2009-08-27 WO disclosed
US-7435861-B2 carotenes or xanthophylls, used as free radical scavengers; cytoprotective agents; oxidation resistance CARDAX PHARMACEUTICALS, INC. (US) 2008-10-14 US disclosed
US-20080221377-A1 Methods for synthesis of carotenoids, including analogs, derivatives, and synthetic and biological intermediates CARDAX PHARMACEUTICALS, INC. 2008-09-11 US disclosed
US-20080064898-A1 Method for Producing Oxygen-Containing Compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-03-13 US disclosed
EP-1879902-A2 METHODS FOR SYNTHESIS OF CAROTENOIDS, INCLUDING ANALOGS, DERIVATIVES, AND SYNTHETIC AND BIOLOGICAL INTERMEDIATES Hawaii Biotech, Inc. (US) 2008-01-23 EP disclosed
WO-2007147163-A2 COMPOSITIONS COMPRISING CAROTENOID ANALOGS OR DERIVATIVES AND METHODS FOR SYNTHESIS CARDAX PHARMACEUTICALS, INC. (US) 2007-12-21 WO disclosed
EP-0412551-A2 Process for producing alpha, beta-unsaturated aldehyde KURARAY CO., LTD. (JP) 1991-02-13 EP disclosed
US-4947001-A Halogenating hydroxysulfone salt KURARAY COMPANY, LTD. (JP) 1990-08-07 US disclosed
EP-0187259-B1 PROCESS FOR PRODUCING VITAMIN A OR ITS CARBOXYLIC ACID ESTERS, AND INTERMEDIATE COMPOUNDS USEFUL FOR THE PROCESS KURARAY CO., LTD. (JP) 1990-06-13 EP disclosed
EP-0348813-A2 Process for producing halogenated sulfone KURARAY CO., LTD. (JP) 1990-01-03 EP disclosed
US-4876400-A DESULFONATION KURARAY CO., LTD. (JP) 1989-10-24 US disclosed
US-4825006-A A-ARYLSULFONYL- KURARAY CO., LTD. (JP) 1989-04-25 US disclosed
US-4745229-A OXIDATION, DECHLORINATION KURARAY COMPANY LTD. (JP) 1988-05-17 US disclosed
EP-0234496-A2 Process for preparing alpha, beta-unsaturated aldehydes Kuraray Co., Ltd. (JP) 1987-09-02 EP disclosed
EP-0187259-A2 Process for producing vitamin A or its carboxylic acid esters, and intermediate compounds useful for the process KURARAY CO., LTD. (JP) 1986-07-16 EP disclosed
US-3931257-A ANTIINFLAMMATORY, ANTIALLERGY HOFFMANN-LA ROCHE INC. (US) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080064898-A1 Method for Producing Oxygen-Containing Compound AOC2, AOX1, CAT ALDH1A1 36/4885ALOX15 312/4885PTPN1 4806/4885
US-20080221377-A1 Methods for synthesis of carotenoids, including analogs, derivatives, and synthetic and biological intermediates HCCS, SQOR, CBR3 ALDH1A1 1671/4885ALOX15 38/4885PTPN1 3786/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.