SCHEMBL9740281

SCHEMBL9740281

O=C(C[C@@H](Cc1cccc2ccccc12)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)c1cccs1)C1CNCCO1

nearest known ligand 0.43

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 20/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10708945 0.88 REN (0.45) REN
SCHEMBL9849454 0.86 REN (0.53) REN
SCHEMBL9740273 0.86 REN (0.53) REN
SCHEMBL10708990 0.79 REN (0.38) REN
SCHEMBL10712236 0.77 REN (0.42) REN
SCHEMBL10711608 0.77 REN (0.41) REN
SCHEMBL10421231 0.76 REN (0.46) REN
SCHEMBL7369317 0.76 REN (0.52) REN
SCHEMBL9740623 0.76 REN (0.47) REN
SCHEMBL10709088 0.75 REN (0.46) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5104869-A Renin inhibitors AMERICAN CYANAMID COMPANY (US) 1992-04-14 — — US disclosed
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