Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 2/20 | 0.49 |
| ▸ | CACNG8 | Q8WXS5 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 2/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 3/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10711968 | 0.76 | RAB9A (0.51) | GRIA1CACNG8RAB9ASMN1; SMN2AHR | |
| SCHEMBL5378136 | 0.75 | CA12 (0.40) | GRIA1CACNG8RAB9ASMN1; SMN2AHR | |
| SCHEMBL10712589 | 0.75 | GRIA1 (0.52) | GRIA1CACNG8RAB9ASMN1; SMN2AHR | |
| SCHEMBL4408889 | 0.73 | TDP2 (0.65) | GRIA1CACNG8AHRPDK2TDP2 | |
| SCHEMBL12992123 | 0.73 | GRIA1 (0.41) | GRIA1CACNG8AHRPDK2TDP2 | |
| SCHEMBL25746058 | 0.73 | GSK3B (0.38) | GRIA1CACNG8AHRPDK2TDP2 | |
| SCHEMBL29622074 | 0.72 | CCNB2 (0.54) | GRIA1CACNG8AHRPDK2GSK3B | |
| SCHEMBL152281 | 0.72 | CCNB2 (0.54) | GRIA1CACNG8AHRPDK2GSK3B | |
| SCHEMBL9834730 | 0.70 | GSK3B (0.42) | TDP2GSK3BCDK5GSK3ACCNB2 | |
| SCHEMBL6328529 | 0.70 | BRD4 (0.54) | GRIA1CACNG8AHRPDK2TDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670566-A | ANTIIFLAMMATORY AGENTS, ANTICOAGULANTS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1987-06-02 | — | — | US | disclosed |
| US-4440785-A | Methods of using 2-aminobiphenylacetic acids, esters, and metal salts thereof to treat inflammation | A. H. ROBINS COMPANY, INC. (US) | 1984-04-03 | — | — | US | disclosed |