Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10712773 | 0.82 | TDP1 (0.42) | TDP1CYP3A4ALDH1A1KMT2AGAA | |
| SCHEMBL19370850 | 0.82 | PGR (0.50) | TDP1CYP3A4ALDH1A1KMT2AGAA | |
| SCHEMBL11427311 | 0.82 | PGR (0.50) | TDP1CYP3A4ALDH1A1KMT2AGAA | |
| SCHEMBL10712283 | 0.77 | PGR (0.49) | TDP1CYP3A4ALDH1A1KMT2AMAPT | |
| SCHEMBL10713389 | 0.75 | PGR (0.55) | TDP1CYP3A4ALDH1A1KMT2AMAPT | |
| SCHEMBL10711722 | 0.75 | PBRM1 (0.35) | ALDH1A1KMT2AMAPTMEN1POLB | |
| SCHEMBL10712231 | 0.73 | PGR (0.62) | KMT2AGAALMNAMAPTPGR | |
| SCHEMBL30683694 | 0.72 | ALDH1A1 (0.72) | TDP1CYP3A4ALDH1A1KMT2ATSHR | |
| SCHEMBL10715133 | 0.72 | PGR (0.72) | MAPTPGRTDP2 | |
| SCHEMBL10710481 | 0.67 | PGR (0.51) | ALDH1A1KMT2ALMNAMAPTPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670566-A | ANTIIFLAMMATORY AGENTS, ANTICOAGULANTS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1987-06-02 | — | — | US | disclosed |
| US-4440785-A | Methods of using 2-aminobiphenylacetic acids, esters, and metal salts thereof to treat inflammation | A. H. ROBINS COMPANY, INC. (US) | 1984-04-03 | — | — | US | disclosed |