SCHEMBL10716638

SCHEMBL10716638

O=C(O)c1c[nH]n2cnnc12

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
KDM4E B2RXH2 1/20 0.41
DDO Q99489 1/20 0.40
ATM Q13315 1/20 0.33
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33
NOTUM Q6P988 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31293979 0.72 KDM4E (0.41) ALDH1A1KDM4ENOTUM
SCHEMBL10030819 0.63 DHODH (0.49) ALDH1A1KDM4EDDO
SCHEMBL104464 0.61 KDM4E (0.59) ALDH1A1KDM4EDDOKMT2AMEN1
SCHEMBL104901 0.61 KDM4E (0.40) ALDH1A1KDM4EDDOKMT2A
SCHEMBL70047 0.58 NOTUM (0.65) ALDH1A1KDM4EKMT2ANOTUM
SCHEMBL15758318 0.57 NOTUM (0.56) ALDH1A1KDM4EKMT2AMEN1NOTUM
SCHEMBL70537 0.56 HCAR2 (0.46) ALDH1A1KDM4EKMT2AMEN1NOTUM
SCHEMBL17865708 0.54
SCHEMBL6554973 0.51
Pyromellitic Acid SCHEMBL22443 0.51 ALDH1A1 (0.53) ALDH1A1KDM4EKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-62033178-A None JP disclosed
JP-62033177-A None JP disclosed
JP-S6233178-A PRODUCTION OF 1H-PYRAZOLO(3,2-C)-1,2,4-TRIAZOLE-7-CARBOXYLATE COMPOUND KONISHIROKU PHOTO IND CO LTD 1987-02-13 JP disclosed
JP-S6233177-A PRODUCTION OF 1H-PYRAZOLO(3,2-C)-1,2,4-TRIAZOLE COMPOUND KONISHIROKU PHOTO IND CO LTD 1987-02-13 JP disclosed