Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | AGER | Q15109 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15558806 | 0.84 | DYRK1B (0.34) | KDM4EL3MBTL1 | |
| SCHEMBL18740147 | 0.84 | DYRK1B (0.34) | KDM4EL3MBTL1 | |
| SCHEMBL10716638 | 0.72 | ALDH1A1 (0.41) | KDM4EALDH1A1NOTUM | |
| SCHEMBL6287856 | 0.64 | NUDT1 (0.33) | NAPRT | |
| SCHEMBL15266367 | 0.64 | KDM5A (0.40) | KDM4EALDH1A1KDM5AMAPTLMNA | |
| SCHEMBL1419899 | 0.63 | KDM4E (0.50) | KDM4EALDH1A1TDP1L3MBTL1CYP3A4 | |
| SCHEMBL20199464 | 0.63 | GSK3A (0.42) | KDM4EALDH1A1TDP1L3MBTL1CYP3A4 | |
| SCHEMBL7871163 | 0.62 | KDM4E (0.40) | KDM4EALDH1A1TDP1KDM4CL3MBTL1 | |
| SCHEMBL2499260 | 0.62 | KDM4E (0.40) | KDM4EALDH1A1TDP1KDM4CL3MBTL1 | |
| SCHEMBL2550512 | 0.62 | KDM4E (0.37) | KDM4EALDH1A1TDP1KDM4CKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4724439-A1 | HETEROARYL DERIVATIVES AS DDRS INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2026-04-15 | — | — | EP | disclosed |
| WO-2024251855-A1 | HETEROARYL DERIVATIVES AS DDRS INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-12-12 | — | — | WO | disclosed |