Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8177791 | 0.83 | POLB (0.56) | CYP3A4CYP2C9POLBTDP1L3MBTL1 | |
| SCHEMBL9825414 | 0.81 | CYP2C9 (0.48) | CYP3A4CYP2C9LMNAKMT2A | |
| SCHEMBL9496095 | 0.78 | MEN1 (0.51) | CYP3A4CYP2C9LMNAKMT2A | |
| SCHEMBL9714520 | 0.77 | POLB (0.70) | CYP3A4CYP2C9POLBABCB1 | |
| SCHEMBL9824961 | 0.74 | SMN1; SMN2 (0.49) | POLBTDP1L3MBTL1KMT2A | |
| SCHEMBL9877055 | 0.74 | GPR27 (0.43) | L3MBTL1ABCB1KMT2A | |
| SCHEMBL10721764 | 0.73 | HPGD (0.55) | CYP3A4POLBABCB1 | |
| SCHEMBL9652356 | 0.73 | RAB9A (0.54) | CYP2C9POLBL3MBTL1LMNAKMT2A | |
| SCHEMBL9426049 | 0.73 | HTT (0.50) | CYP3A4CYP2C9LMNA | |
| SCHEMBL13678990 | 0.72 | EPHX2 (0.45) | POLBTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236618-A2 | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |