Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10717700 | 0.82 | ALDH1A1 (0.45) | KDM4EPKMNFE2L2ALDH1A1MEN1 | |
| SCHEMBL10718843 | 0.68 | ALDH1A1 (0.49) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL114270 | 0.66 | CYP2D6 (0.48) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28358475 | 0.66 | CYP2D6 (0.51) | KDM4EALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL11761496 | 0.65 | SMN1; SMN2 (0.41) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL761379 | 0.65 | ALDH1A1 (0.56) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2118378 | 0.64 | ALDH1A1 (0.82) | KDM4EPKMALDH1A1MEN1KMT2A | |
| SCHEMBL10661311 | 0.64 | PTGS2 (0.56) | KDM4EPKMNFE2L2ALDH1A1MEN1 | |
| SCHEMBL10203520 | 0.64 | POLB (0.39) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5630877 | 0.64 | BRD4 (0.48) | KDM4EALDH1A1KMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4659727-A | ANTIARTHRITIC AGENTS | MAY & BAKER LIMITED (GB) | 1987-04-21 | — | — | US | disclosed |
| EP-0174832-A2 | Ethene derivatives | MAY & BAKER LIMITED (GB) | 1986-03-19 | — | — | EP | disclosed |