Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.41 |
| ▸ | DRD1 | P21728 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14290472 | 0.79 | CYP2D6 (0.48) | CYP2D6CYP2C19ALDH1A1CHRM2ADRA2A | |
| SCHEMBL2861141 | 0.78 | CYP2D6 (0.42) | CYP2D6CYP2C19ALDH1A1CHRM2ADRA2A | |
| SCHEMBL2702055 | 0.78 | ALDH1A1 (0.43) | CYP2D6CYP2C19ALDH1A1CHRM2ADRA2A | |
| Bromide SCHEMBL9508759 | 0.78 | CYP2D6 (0.47) | CYP2D6CYP2C19ALDH1A1CHRM2ADRA2A | |
| SCHEMBL25312219 | 0.78 | CYP2D6 (0.47) | CYP2D6CYP2C19ALDH1A1CHRM2ADRA2A | |
| Formic Acid SCHEMBL27994873 | 0.78 | CYP2D6 (0.47) | CYP2D6CYP2C19ALDH1A1CHRM2ADRA2A | |
| SCHEMBL1855483 | 0.76 | CYP2D6 (0.46) | CYP2D6CYP2C19ALDH1A1CHRM2ADRA2A | |
| SCHEMBL22048451 | 0.76 | ALDH1A1 (0.46) | CYP2D6CYP2C19ALDH1A1CHRM2ADRA2A | |
| SCHEMBL28807709 | 0.76 | POLB (0.43) | CYP2D6CYP2C19ALDH1A1CHRM2ADRA2A | |
| SCHEMBL12879844 | 0.76 | CYP2D6 (0.46) | CYP2D6CYP2C19ALDH1A1CHRM2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057737-A | Method for directly preparing 3-acyl imidazole [1,5-a ] pyridine by one-step secondary amination reaction of [4+1] ketone methyl | 安徽科技学院 | 2022-02-18 | — | — | CN | claimed |
| US-7479575-B2 | Method for preparing para-phenyl alkynyl benzaldehydes | LABORATOIRES SERONO SA (CH) | 2009-01-20 | — | — | US | claimed |
| US-20080108849-A1 | Method For Preparing Para-Phenyl Alkynyl Benzaldehydes | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2008-05-08 | — | — | US | claimed |
| EP-1675813-B1 | METHOD FOR PREPARING PARA-PHENYL ALKYNYL BENZALDEHYDES | SERONO LAB (CH) | 2007-12-19 | — | — | EP | claimed |
| JP-2007508277-A | — | — | 2007-04-05 | — | — | JP | claimed |
| EP-1675813-A1 | METHOD FOR PREPARING PARA-PHENYL ALKYNYL BENZALDEHYDES | Applied Research Systems ARS Holding N.V. (NL) | 2006-07-05 | — | — | EP | claimed |
| WO-2005037758-A1 | METHOD FOR PREPARING PARA-PHENYL ALKYNYL BENZALDEHYDES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2005-04-28 | — | — | WO | claimed |
| US-6352985-B1 | CARDIOVASCULAR DISORDERS OR GASTROINTESTINAL DISORDERS, DIABETES (TYPE II DIABETES), DIABETIC COMPLICATIONS METHOD FOR LOWERING THE BLOOD SUGAR LEVEL OF A PATIENT, | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-05 | — | — | US | claimed |
| EP-0882718-A1 | BENZIMIDAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-12-09 | — | — | EP | claimed |
| CN-111205198-B | Method for preparing formamide compound by catalyzing carbon dioxide hydrogenation through porous material | 复旦大学 | 2023-08-01 | — | — | CN | disclosed |
| CN-114057737-A | Method for directly preparing 3-acyl imidazole [1,5-a ] pyridine by one-step secondary amination reaction of [4+1] ketone methyl | 安徽科技学院 | 2022-02-18 | — | — | CN | disclosed |
| CN-114057737-A | Method for directly preparing 3-acyl imidazole [1,5-a ] pyridine by one-step secondary amination reaction of [4+1] ketone methyl | 安徽科技学院 | 2022-02-18 | — | — | CN | disclosed |
| EP-3318561-B1 | HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC (US) | 2021-12-22 | — | — | EP | disclosed |
| EP-3318561-B1 | HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC (US) | 2021-12-22 | — | — | EP | disclosed |
| US-5256666-A | Pesticides | BASF AKTIENGESELLSCHAFT (DE) | 1993-10-26 | — | — | US | disclosed |
| EP-0543238-A1 | 3-Isoxazolylphenyl-compounds, their preparation and application | BASF Aktiengesellschaft (DE) | 1993-05-26 | — | — | EP | disclosed |
| US-5151441-A | Insecticides or miticides | BASF AKTIENGESELLSCHAFT (DE) | 1992-09-29 | — | — | US | disclosed |
| EP-0457204-A1 | 3-Isoxazolylbenzylesters, their preparation and utilization | BASF Aktiengesellschaft (DE) | 1991-11-21 | — | — | EP | disclosed |
| EP-0414059-A1 | Dihalogenovinylbenzylesters, process and starting material for their preparation and their utilization for the control of parasites | BASF Aktiengesellschaft (DE) | 1991-02-27 | — | — | EP | disclosed |
| EP-0310676-A1 | LIQUID-CRYSTAL DERIVATIVES OF 2,5-DISUBSTITUTED PYRIDINE AS COMPONENTS OF LIQUID-CRYSTAL MATERIAL, AND A LIQUID-CRYSTAL MATERIAL | PAVLJUCHENKO, Assya Iosifovna (RU) | 1989-04-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108849-A1 | Method For Preparing Para-Phenyl Alkynyl Benzaldehydes | TNNC1, CPT1B, MUSK | CYP2D6 378/4885CYP2C19 590/4885ALDH1A1 200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.