Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 4/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP8 | P22894 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | IL1RN | P18510 | 2/20 | 0.39 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 4/20 | 0.39 |
| ▸ | CTSD | P07339 | 2/20 | 0.39 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 2/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11012642 | 1.00 | ANPEP (0.41) | ANPEPERAP2ERAP1MMP9MMP8 | |
| SCHEMBL10725310 | 0.88 | REN (0.53) | ANPEPERAP1MMP9MMP8MMP2 | |
| SCHEMBL10724555 | 0.88 | REN (0.53) | ANPEPERAP1MMP9MMP8MMP2 | |
| SCHEMBL10720793 | 0.88 | REN (0.53) | ANPEPERAP1MMP9MMP8MMP2 | |
| SCHEMBL10724261 | 0.87 | ANPEP (0.42) | ANPEPERAP2ERAP1MMP9MMP8 | |
| Bromide SCHEMBL10976755 | 0.83 | MMP9 (0.45) | ANPEPERAP2MMP9MMP8MMP2 | |
| Bromide SCHEMBL10635874 | 0.83 | MMP9 (0.45) | ANPEPERAP2MMP9MMP8MMP2 | |
| SCHEMBL7274793 | 0.82 | REN (0.46) | ANPEPERAP2ERAP1MMP9MMP8 | |
| SCHEMBL10724617 | 0.81 | REN (0.51) | ANPEPERAP1MMP9MMP8MMP2 | |
| SCHEMBL10720911 | 0.81 | REN (0.51) | ANPEPERAP1MMP9MMP8MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4698329-A | HYPOTENSIVE AGENTS | SANKYO COMPANY, LIMITED (JP) | 1987-10-06 | — | — | US | disclosed |
| EP-0152255-A2 | New renin-inhibitory peptides and their use | SANKYO COMPANY LIMITED (JP) | 1985-08-21 | — | — | EP | disclosed |