Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 4/20 | 0.39 |
| ▸ | RXRB | P28702 | 4/20 | 0.39 |
| ▸ | RXRG | P48443 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | GLP1R | P43220 | 1/20 | 0.36 |
| ▸ | GCGR | P47871 | 1/20 | 0.36 |
| ▸ | GIPR | P48546 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10722451 | 0.89 | MAPT (0.52) | MAPTALDH1A1KDM4ENOTUMPOLB | |
| SCHEMBL10720144 | 0.85 | ALDH1A1 (0.44) | MAPTALDH1A1KDM4ENOTUMMALT1 | |
| SCHEMBL10719033 | 0.85 | MAPT (0.45) | MAPTALDH1A1KDM4ERXRACYP2C9 | |
| SCHEMBL10721324 | 0.82 | DRD2 (0.46) | MAPTALDH1A1KDM4EPOLB | |
| SCHEMBL10719947 | 0.81 | MAPT (0.48) | MAPTALDH1A1KDM4ERXRARXRB | |
| SCHEMBL10360378 | 0.76 | PPARD (0.44) | MAPTALDH1A1KDM4EPPARGPPARA | |
| SCHEMBL31301425 | 0.74 | TP53 (0.44) | MAPTNOTUMCYP2C9POLB | |
| SCHEMBL16030472 | 0.73 | FFAR1 (0.52) | CYP2C9PPARGPPARAPPARD | |
| SCHEMBL10720115 | 0.73 | MEN1 (0.46) | MAPTALDH1A1KDM4ENOTUMRXRA | |
| SCHEMBL11605293 | 0.73 | L3MBTL1 (0.61) | ALDH1A1PPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0227284-A1 | Plant Growth regulating triazoles | ELI LILLY AND COMPANY (US) | 1987-07-01 | — | — | EP | disclosed |