Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | FABP3 | P05413 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10719033 | 0.84 | MAPT (0.45) | MAPTALDH1A1KDM4EL3MBTL1RXRA | |
| SCHEMBL6616555 | 0.82 | CYP1A2 (0.42) | MAPTALDH1A1KDM4EPKMLMNA | |
| SCHEMBL10721964 | 0.81 | MAPT (0.47) | MAPTALDH1A1KDM4ERXRARXRB | |
| SCHEMBL4548446 | 0.80 | FFAR1 (0.48) | MAPTALDH1A1KDM4EPTGS2L3MBTL1 | |
| SCHEMBL6616454 | 0.77 | P2RX7 (0.43) | MAPTALDH1A1KDM4EPTGS2RXRA | |
| SCHEMBL10360298 | 0.76 | MAPT (0.42) | MAPTALDH1A1KDM4EPTGS2L3MBTL1 | |
| SCHEMBL6615172 | 0.75 | RAB9A (0.44) | MAPTALDH1A1KDM4EPTGS2L3MBTL1 | |
| SCHEMBL1807043 | 0.75 | L3MBTL1 (0.72) | MAPTALDH1A1L3MBTL1GAALMNA | |
| SCHEMBL31301332 | 0.75 | MAPT (0.55) | MAPTALDH1A1PTGS2L3MBTL1PKM | |
| SCHEMBL6615927 | 0.74 | P2RX7 (0.40) | MAPTALDH1A1KDM4EPTGS2RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0227284-A1 | Plant Growth regulating triazoles | ELI LILLY AND COMPANY (US) | 1987-07-01 | — | — | EP | disclosed |